Chlamydiae modulate gamma interferon, interleukin-1 beta, and tumor necrosis factor alpha receptor expression in HeLa cells.
Chlamydiae modulate gamma interferon, interleukin-1 beta, and tumor necrosis factor alpha receptor expression in HeLa cells.
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衣原体调节 HeLa 细胞中的 γ 干扰素、白细胞介素 1 β 和肿瘤坏死因子 α 受体的表达。
DOI：
10.1128/iai.74.4.2482-2486.2006
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发表时间：
2006
影响因子：
3.1
通讯作者：
Carlin,JosephM
中科院分区：
文献类型：
--
作者：
Shirey,KariAnn;Carlin,JosephM
发现鹦鹉鹦鹉衣原体可调节上皮细胞中参与吲哚胺双加氧酶协同诱导的细胞因子受体的受体表达。即使在灭活衣原体中，受体表达也有所增加，这表明衣原体抗原而不是感染产物对细胞因子受体表达的上调起重要作用。
Chlamydia psittaciwas found to modulate receptor expression for the cytokine receptors that are involved in the synergistic induction of indoleamine dioxygenase in epithelial cells. Increases in receptor expression were seen even with inactivatedChlamydia, suggesting that chlamydial antigens and not products of infection are important for up-regulating cytokine receptor expression.