Epidemiologic characteristics of haemorrhagic fever with renal syndrome in Mainland China from 2006 to 2010
Epidemiologic characteristics of haemorrhagic fever with renal syndrome in Mainland China from 2006 to 2010
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DOI：
10.5365/wpsar.2011.2.2.007
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发表时间：
2012-01-01
影响因子：
1
通讯作者：
Wang, Shiwen
中科院分区：
文献类型：
--
作者：
Huang, Xiaoxia;Yin, Hongmei;Wang, Shiwen
目的：为制定有效的肾综合征出血热（HFRS）防控策略，分析2006 - 2010年中国大陆HFRS病例的流行病学特征和趋势。分析的病例包括临床病例和实验室确诊病例。按时间、地区和职业提取数据进行统计分析;发病率直接从CNDRS获得。结果：2006 - 2010年HFRS发病15 098例，2009 - 2010年发病8 745例，呈下降趋势，2010年发病9 526例，呈小幅上升趋势。2006年至2010年，31个省中有29个报告了HFRS病例。东北的黑龙江、吉林、辽宁、东部的山东和中部的陕西等5个省为高发区。病例季节分布呈双峰型，春季和冬季为病例高峰期。青年男性农民是HFRS的易感人群。早期到中年的成年人（20-50岁）代表了HFRS病例的最大群体。结论：中国HFRS病例的总体数量呈下降趋势，可能是由于在过去25年中实施的国家疫苗和啮齿动物病媒控制计划。然而，这一趋势在过去五年中有所减缓。高流行地区和高危人群仍然存在，将受益于进一步有针对性的预防战略。
Objective: To design effective prevention and control strategies for haemorrhagic fever with renal syndrome (HFRS) in Mainland China, we evaluated the epidemiologic characteristics and trends of HFRS cases reported between 2006 and 2010.Methods: HFRS data from 1970 to 2010 were obtained from the China Notifiable Disease Reporting System (CNDRS). The cases analysed included clinical cases and laboratory-confirmed cases. Data was extracted for statistical analysis by time, region and profession; the incidence rate was obtained directly from CNDRS. In this study, we analysed the morbidity and mortality data of HFRS from 2006 to 2010.Results: HFRS cases trended downward from 2006 (15 098) to 2009 (8745), but exhibited a slight increase in 2010 (9526). Twenty-nine of 31 provinces reported HFRS cases between 2006 and 2010. Five provinces, namely, Heilongjiang, Jilin and Liaoning in the North-east, Shandong in the east, and Shaanxi in the central part of China, were characterized as high-endemic areas. Seasonal case distribution was bimodal, with peaks of cases in spring and winter. Young male farmers were the most susceptible population to HFRS. Early- to middle-aged adults (20-50 years old) represented the largest groups of HFRS cases.Conclusion: The overall number of cases of HFRS in China has trended downward possibly due to national vaccine and rodent vector control programmes implemented in the past 25 years. However, this trend slowed down in the last five years. High-endemic regions and at-risk population groups still exist and will benefit from further targeted prevention strategies.