Sample treatment for protein identification by mass spectrometry-based techniques
Sample treatment for protein identification by mass spectrometry-based techniques
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DOI：
10.1016/j.trac.2006.05.015
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发表时间：
2006-11-01
影响因子：
13.1
通讯作者：
Capelo, J. L.
中科院分区：
文献类型：
--
作者：
Lopez-Ferrer, D.;Canas, B.;Capelo, J. L.
蛋白质的快速鉴定对于分析界来说至关重要。蛋白质生物标志物的发现，为医学诊断或药理学目的正在成为最热门的研究课题之一。此外，蛋白质的快速鉴定可以帮助明确的细菌和病毒检测。此外，细菌的快速鉴定可用于打击生物恐怖主义。因此，最近出现了新的分析方法，目的是使蛋白质分析尽可能快速和可靠。在这篇文章中，我们批判性地回顾了蛋白质鉴定样品处理的新趋势，并对这一有前途的分析领域的未来前景进行了评论。(c)2006爱思唯尔有限公司保留所有权利。
Rapid identification of proteins is of primary importance for the analytical community. Protein-biomarker discovery for medical diagnostics or pharmacological purposes is becoming one of the hottest research topics. Moreover, rapid identification of proteins can help unambiguous bacterial and virus detection. In addition, the fast identification of bacteria can be used to beat bioterrorism. As a consequence, new analytical methodologies have emerged recently with the aim of making protein analysis as fast and as confident as possible. In this article, we critically review the new trends in sample treatment for protein identification and comment on the prospects for the future in this promising analytical area. (c) 2006 Elsevier Ltd. All rights reserved.