Projections from bed nuclei of the stria terminalis, posterior division: Implications for cerebral hemisphere regulation of defensive and reproductive behaviors
Projections from bed nuclei of the stria terminalis, posterior division: Implications for cerebral hemisphere regulation of defensive and reproductive behaviors
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DOI：
10.1002/cne.20002
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发表时间：
2004-04-12
影响因子：
2.5
通讯作者：
Swanson, LW
中科院分区：
文献类型：
--
作者：
Dong, HW;Swanson, LW
终纹床核的后部有三个主要核：主核、束间核和横核，它们接受来自内侧杏仁核的地形有序的输入。用菜豆-白细胞凝集素法测定了雄性大鼠各核轴突投射的总体模式。这些核团一起投射到杏仁内侧核、相邻的外侧隔核、丘脑核和无名质、行为控制柱的下丘脑部分以及控制神经内分泌和自主反应模式的下丘脑室周区。主核优先支配控制生殖行为和内脏反应的隔区和下丘脑区，证实了Gu等人的类似分析（J Comp Neurol [2003] 460：542-562）。与此相反，束间核和横核差异支配隔区和下丘脑区域，控制防御以及生殖行为。此外，横核项目显着中脑部分的行为控制列有关觅食/探索行为。所有三个后分裂核也投射到丘脑皮质反馈回路（通过连合核和室旁核）。这些结构数据可能被解释为表明，床核后分裂的皮质纹状体苍白球系统的一部分（苍白球）参与控制两个主要类别的社会（防御和生殖）行为。(C)2004 Wiley-Liss，Inc.
The posterior division of the bed nuclei of the stria terminalis has three major nuclei: principal, interfascicular, and transverse, which receive topographically ordered inputs from the medial amygdalar nucleus. The overall pattern of axonal projections from each nucleus was determined in male rats with the Phaseolus vulgaris-leucoagglutinin method. Together, these nuclei project topographically back to the medial amygdalar nucleus, to the adjacent lateral septal nucleus, to the nucleus accumbens and substantia innominata, to hypothalamic parts of the behavior control column, and to the hypothalamic periventricular region, which controls patterned neuroendocrine and autonomic responses. The principal nucleus preferentially innervates septal and hypothalamic regions that control reproductive behavior and visceromotor responses, confirming a similar analysis by Gu et al. (J Comp Neurol [2003] 460:542-562). In contrast, the interfascicular and transverse nuclei differentially innervate septal and hypothalamic regions that control defensive as well as reproductive behaviors. In addition, the transverse nucleus projects significantly to midbrain parts of the behavior control column concerned with foraging/exploratory behavior. All three posterior division nuclei also project to thalamocortical feedback loops (by means of the nucleus reuniens and paraventricular nucleus). These structural data may be interpreted to suggest that the bed nuclei posterior division forms part (pallidal) of a corticostriatopallidal system involved in controlling two major classes of social (defensive and reproductive) behavior. (C) 2004 Wiley-Liss, Inc.