Preparation of ferrocene immobilized metal–organic-framework modified electrode for the determination of acetaminophen
Preparation of ferrocene immobilized metal–organic-framework modified electrode for the determination of acetaminophen
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DOI：
10.1039/c2ay26061a
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发表时间：
2012-11
影响因子：
3.1
通讯作者：
Zidong Chang;Nansha Gao;Yijun Li;Xiwen He
中科院分区：
文献类型：
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作者：
Zidong Chang;Nansha Gao;Yijun Li;Xiwen He
通过一步程序即可轻松制备二茂铁固定 MOF 改性石墨电极。所得电极在支持电解质溶液中表现出非常良好且稳定的电化学行为。对乙酰氨基酚可以在修饰电极上被电催化氧化。峰值电流在 1.0 × 10−8 至 2.0 × 10−5 mol L−1 浓度范围内表现出良好的线性，检测限为 6.4 × 10−9 mol L−1 (3σ)。该电极可用于药物和血清样品中对乙酰氨基酚的测定，结果满意。
A ferrocene-immobilized MOF-modified graphite electrode was prepared easily by a one-step procedure. The resulting electrodes showed very good and stable electrochemical behaviour in supporting electrolyte solutions. Acetaminophen could be oxidized electrocatalytically on the modified electrode. The peak current showed good linearity with concentrations in the range of 1.0 × 10−8 to 2.0 × 10−5 mol L−1 and a detection limit of 6.4 × 10−9 mol L−1 (3σ). The electrode could be applied for the determination of acetaminophen in pharmaceutical and serum samples with satisfactory results.