A Feasible Industrialized Process for Producing High Purity Diacylglycerols with No Contaminants
A Feasible Industrialized Process for Producing High Purity Diacylglycerols with No Contaminants
复制标题
一种可行的工业化生产高纯度无污染物二酰甘油的工艺
DOI：
10.1002/ejlt.201900039
复制
发表时间：
2019-08-22
影响因子：
2.7
通讯作者：
Wang, Yonghua
中科院分区：
文献类型：
--
作者：
Li, Daoming;Qin, Xiaoli;Wang, Yonghua
高纯度二酰基甘油（DAG）的工业生产在世界范围内仍然是一个挑战，因为在DAG生产过程中会形成污染物，例如缩水甘油酯（GE）、3-氯-1，2-丙二醇酯（3-MCPDE）和反式脂肪酸（TFA）。本研究开发了一种可行的工业化生产高纯度无污染的DAGs的工艺，结合酶酯化，三级分子蒸馏，漂白，汽提蒸馏。在填充床反应器中在30 ℃下固定化SMG 1-F278 N催化酯化后，产物含有50.87%的DAG、32.82%的单酰基甘油（MAG）和16.31%的FA。随后分别在150、160和160 ℃下通过三级分子蒸馏纯化所得DAG，接着在65 ℃下在真空（2kPa）下漂白，并在160 ℃下在真空（100 Pa）下干燥。在DAG制备的整个过程中，无法检测到含有GE、3-MCPDE和TFA的污染物。最终的DAG产品含有99.74%的DAG，并显示出良好的质量指标（过氧化值为2.05 mmol kg（-1），且未检测到酸值）。总体而言，本研究提出了一种新的工业策略，生产高纯度和高质量的DAGs，这可能会促进DAGs的再商业化在不久的将来。实际应用：由于其促进健康的特性，在日本和美国广泛销售的DAGs作为健康食用油，然而，在检测到潜在致癌物GE严重超过DAGs的允许值后，DAGs的销售被停止。本研究提出了一种可行的工业化生产高纯度和高质量的DAG的工艺，不含污染物，包括GE，3-MCPDE和TFA。固定化SMG 1-F278 N填充填充床反应器生产DAG，可使用半年以上，酯化活性无明显损失，是一种经济的工艺。总的来说，提出的经济策略可能会为未来生产可食用，可用和安全的DAG提供启示。提出了一种工业化生产无污染高纯度甘油二酯的可行工艺。总的来说，提出的经济策略可能会为未来生产可食用，可用和安全的DAG提供启示。
Industrial production of high purity diacylglycerols (DAGs) is still a challenge around the world because of contaminant formation during DAG production, such as glycidyl esters (GEs), 3-chloro-1,2-propanediol esters (3-MCPDEs), and trans fatty acids (TFAs). This study develops a feasible industrialized process for producing high purity DAGs with no contaminants by combining enzymatic esterification, three-stage molecular distillation, bleaching, and stream stripping deodorization. After immobilized SMG1-F278N-catalyzed esterification in a packed bed reactor at 30 degrees C, the product contains 50.87% DAGs, 32.82% monoacylglycerols (MAGs), and 16.31% FAs. The resultant DAGs are subsequently purified by a three-stage molecular distillation at 150, 160, and 160 degrees C, respectively, followed by bleaching under vacuum (2 kPa) at 65 degrees C and deodorization under vacuum (100 Pa) at 160 degrees C. Contaminants containing GEs, 3-MCPDEs, and TFAs are undetectable throughout the whole process of DAG preparation. The final DAG product contains 99.74% DAGs and shows good quality indices (peroxide value of 2.05 mmol kg(-1) and undetectable acid value). Overall, this study proposes a new industrial strategy for the production of DAGs with high purity and quality, which may promote the re-commercialization of DAGs in the near future. Practical Applications: DAGs were widely sold in Japan and America as healthy cooking oils owing to their health promoting properties, however, sales of DAGs were stopped after the detection of the potential carcinogen of GEs seriously exceeded the allowed value in DAGs. This study proposes a feasible industrialized process for producing high purity and quality DAGs with no contaminants including GEs, 3-MCPDEs, and TFAs. The immobilized SMG1-F278N that fills in packed bed reactor for DAG production can be used for at least a half year without significant loss in its esterification activity, indicating that the proposed process is an economical process. Overall, the proposed economical strategy may shed light for future production of edible, available, and safe DAGs. A feasible industrialized process for producing high purity diacylglycerols (DAGs) with no contaminants is proposed. Overall, the proposed economical strategy may shed light for future production of edible, available, and safe DAGs.