IDENTIFICATION OF MIF AS A NEW PITUITARY-HORMONE AND MACROPHAGE CYTOKINE AND ITS ROLE IN ENDOTOXIC-SHOCK
IDENTIFICATION OF MIF AS A NEW PITUITARY-HORMONE AND MACROPHAGE CYTOKINE AND ITS ROLE IN ENDOTOXIC-SHOCK
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DOI：
10.1016/0165-2478(94)00152-9
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发表时间：
1994-12-01
影响因子：
4.4
通讯作者：
BUCALA, R
中科院分区：
文献类型：
--
作者：
BUCALA, R
The protein mediator described originally as macrophage migration inhibitory factor has been ''rediscovered'' to be both a novel pituitary hormone and a pro-inflammatory, macrophage-derived cytokine. MIF plays a pivotal role in the host response to endotoxic shock and appears to serve as a pituitary ''stress'' hormone that regulates systemic inflammatory responses.
