Electrical Stimulation of Somatic Afferent Nerves in the Foot Increases Bladder Capacity in Healthy Human Subjects
Electrical Stimulation of Somatic Afferent Nerves in the Foot Increases Bladder Capacity in Healthy Human Subjects
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DOI：
10.1016/j.juro.2013.10.024
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发表时间：
2014-04-01
影响因子：
6.6
通讯作者：
Tai, Changfeng
中科院分区：
文献类型：
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作者：
Chen, Mang L.;Chermansky, Christopher J.;Tai, Changfeng
目的：我们确定是否在足部的躯体传入神经的电刺激可以延迟膀胱充盈的感觉，并增加膀胱容量在健康人没有过度活动bulletin.Materials和方法：8名受试者进行了90分钟的足部刺激皮肤表面电极连接到经皮电神经刺激器。电极被连接到脚底。受试者完成3天排尿日记，在此期间，在第2天施加足部刺激。刺激参数为脉冲频率5 Hz，矩形波形脉冲宽度0.2毫秒，强度为诱导脚趾抽搐所需的最小刺激电流的2至6倍。刺激强度由每名受试者设置为最大水平，不会引起不适。受试者提供了500至1,000毫升的水喝stimulation.Results：平均+/- SE体积每次排尿是350 +/- 22毫升，在24小时前足部刺激。刺激后5小时内，排尿量平均增加至547 +/- 52 ml（p
Purpose: We determined whether electrical stimulation of somatic afferent nerves in the foot could delay bladder filling sensations and increase bladder capacity in healthy humans without overactive bladder.Materials and Methods: Eight subjects underwent 90-minute foot stimulation using skin surface electrodes connected to a transcutaneous electrical nerve stimulator. The electrodes were attached to the bottom of the foot. Subjects completed a 3-day voiding diary, during which foot stimulation was applied on day 2. Stimulation parameters were pulse frequency 5 Hz, rectangular waveform pulse width 0.2 milliseconds and intensity 2 to 6 times the minimal stimulation current necessary to induce toe twitch. Stimulation intensity was set by each subject to a maximal level without causing discomfort. Subjects were provided with 500 to 1,000 ml of water to drink during stimulation.Results: Average +/- SE volume per void was 350 +/- 22 ml during the 24 hours before foot stimulation. This voided volume increased to a mean of 547 +/- 52 ml for up to 5 hours after stimulation (p