Effect of aging aqueous nitrogen mustard on white blood cell count, body weight, and Walker 256 tumor in the rat.
Effect of aging aqueous nitrogen mustard on white blood cell count, body weight, and Walker 256 tumor in the rat.
复制标题
老化氮芥水对大鼠白细胞计数、体重和 Walker 256 肿瘤的影响。
DOI：
10.1139/o63-050
复制
发表时间：
1963
期刊：
影响因子：
--
通讯作者：
J. McCredie
中科院分区：
文献类型：
--
作者：
W. Inch;J. McCredie
将氮芥水溶液老化3天并没有显著改变其降低大鼠白色血细胞计数、体重或已建立的步行者256肿瘤生长的能力。白色血细胞计数减少与肿瘤生长抑制之间存在直接关系，但体重下降与肿瘤生长之间无直接关系。酸性的水氮芥（0.5毫克/毫升）随时间呈指数增加，长达100天，但不相关的能力，以减少白色血细胞计数，体重，或肿瘤生长。
Aging an aqueous solution of nitrogen mustard up to 3 days did not alter significantly its ability to decrease the white blood cell count, body weight, or the growth of the established Walker 256 tumor in the rat. There was a direct relationship between the decrease in white blood cell count and depression of tumor growth but not between the depression of body weight and tumor growth. The acidity of aqueous nitrogen mustard (0.5 mg/ml) increased exponentially with time up to 100 days but was not related to the ability to decrease the white blood cell count, body weight, or tumor growth.