Declines in traditional marine food intake and vitamin D levels from the 1960s to present in young Alaska Native women.
Declines in traditional marine food intake and vitamin D levels from the 1960s to present in young Alaska Native women.
复制标题
从1960年代到阿拉斯加年轻的本地妇女的传统海洋食品摄入量和维生素D水平下降。
DOI：
10.1017/s1368980016001853
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发表时间：
2017-07
影响因子：
3.2
通讯作者：
Singleton R
中科院分区：
文献类型：
--
作者：
O'Brien DM;Thummel KE;Bulkow LR;Wang Z;Corbin B;Klejka J;Hopkins SE;Boyer BB;Hennessy TW;Singleton R
测量1960年至今阿拉斯加土著育龄妇女（20-29岁）传统海洋食物摄入量和血清维生素D水平的变化趋势。我们测量了传统食物摄入的生物标志物，δ15N值和维生素D水平，作为25(OH)D3浓度，在阿拉斯加地区标本库中，从20世纪60年代到90年代，每十年选择25个20-29岁女性的血清样本。我们将这些数据与阿拉斯加土著健康研究中心在2000年代和2010年代收集的来自同一地区的20-29岁女性的RBC δ15N值和血清25(OH)D3浓度进行了比较。阿拉斯加西南部的育空-库斯科温三角洲地区。319名阿拉斯加土著妇女，采集标本时年龄在20-29岁之间。从20世纪60年代到90年代，传统海洋食品的摄入量每10年显著下降，然后从90年代到现在保持不变（f5306 = 77.4, p < 0.0001）。从20世纪60年代至今，血清维生素D浓度也有所下降（f4162 = 26.1, p < 0.0001）。20世纪60年代至90年代期间，年轻的阿拉斯加土著妇女对传统海洋食品的消费量显著下降，这与血清维生素D浓度显著下降有关。需要进行研究，以评估在怀孕期间促进传统海洋食品和常规维生素D补充对这一人群的影响。
To measure the trends in traditional marine food intake and serum vitamin D levels in Alaska Native women of childbearing age (20–29 years old) from 1960 to the present. We measured a biomarker of traditional food intake, the δ15N value, and vitamin D level, as 25(OH)D3 concentration, in 100 serum samples from 20–29 year old women archived in the Alaska Area Specimen Bank, selecting 25 per decade from the 1960s to 1990s. We compared these to measurements of RBC δ15N values and serum 25(OH)D3 concentrations from 20–29 year old women from the same region collected during the 2000s and 2010s in a Center for Alaska Native Health Research study. The Yukon Kuskokwim Delta region of Southwest Alaska. 319 Alaska Native women aged 20–29 years at the time of specimen collection. Intake of traditional marine foods, as measured by serum δ15N values, decreased significantly each decade from the 1960s through the 1990s, then remained constant from the 1990s through the present (F5,306 = 77.4, p < 0.0001). Serum vitamin D concentrations also decreased from the 1960s to the present (F4,162 = 26.1, p < 0.0001). Consumption of traditional marine foods by young Alaska Native women dropped significantly between the 1960s and the 1990s and was associated with a significant decline in serum vitamin D concentrations. Studies are needed to evaluate the promotion of traditional marine foods and routine vitamin D supplementation during pregnancy for this population.