Studies in whole body potassium and whole body nitrogen in newly diagnosed diabetics.

Studies in whole body potassium and whole body nitrogen in newly diagnosed diabetics.
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新诊断糖尿病患者全身钾和全身氮的研究。

DOI:
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发表时间:
1976
期刊:
The Quarterly journal of medicine
影响因子:
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通讯作者:
J. Malins
J. Malins
中科院分区:
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文献类型:
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作者:
C. Walsh;N. Soler;H. James;T. C. Harvey;B. J. Thomas;J. Fremlin;M. Fitzgerald;J. Malins

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对18名新诊断的糖尿病患者进行了全身钾和全身氮的连续测量。在开始糖尿病治疗之前进行初步测量,并在治疗开始后进行进一步测量。六名患者需要胰岛素,其余患者要么仅接受饮食治疗(四例),要么接受饮食治疗和口服降糖药治疗。糖尿病控制后,全身钾和全身氮显着增加。论文。这些变化在接受胰岛素治疗的患者中最为明显。与传统代谢平衡研究相比,用于测量体内钾和氮的技术具有相当大的优势,结果表明,在糖尿病控制不佳期间,钾和氮的损失比人们意识到的要大得多。
Serial measurements of whole body potassium and whole body nitrogen were carried out in 18 newly diagnosed diabetcs. Initial measurements were made before treatment of diabetes was commenced, and further measurements were carried out following the start of treatment. Six patients required insulin and the remainder were treated either with diet alone (four cases) or with diet and oral hypoglycaemic agents. Significant increases in whole body potassium and whole body nitrogen were noted following control of diabetes.Thesees. These changes were most marked in the patients treated with insulin. The techniques used for measurement of body potassium and nitrogen offer considerable advantages over conventional metabolic balance studies and the results indicate that the losses of potassium and nitrogen during period of poor diabetic control are much greater than that has been realized.