Improvement in Negative Symptoms and Functioning in Cognitive-Behavioral Social Skills Training for Schizophrenia: Mediation by Defeatist Performance Attitudes and Asocial Beliefs
Improvement in Negative Symptoms and Functioning in Cognitive-Behavioral Social Skills Training for Schizophrenia: Mediation by Defeatist Performance Attitudes and Asocial Beliefs
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DOI：
10.1093/schbul/sbx099
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发表时间：
2018-05-01
影响因子：
6.6
通讯作者：
Worley, Matthew
中科院分区：
文献类型：
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作者：
Granholm, Eric;Holden, Jason;Worley, Matthew
心理社会干预对精神分裂症的阴性症状和功能有显着但适度的影响。确定这些干预措施的变化机制可以为治疗目标提供信息，以加强这些干预措施。许多研究发现精神分裂症患者的不良态度、消极症状和功能之间存在关联。我们以前发现改善经验的阴性症状和功能的认知行为社会技能训练（CBSST）的参与者精神分裂症（N = 149），本研究探讨是否改善CBSST在该试验中介导的失败主义的表现态度和反社会信念的群体效应。在多层次中介分析中，治疗组对经验性阴性症状和功能的影响是通过失败主义态度进行中介的，但反社会信念只对经验性阴性症状起中介作用。研究结果表明，针对功能失调态度的认知行为治疗干预可以改善精神分裂症的阴性症状和功能。
Psychosocial interventions have significant but modest impact on negative symptoms and functioning in schizophrenia. Identifying mechanisms of change in these interventions can inform treatment targets to strengthen these interventions. A number of studies have found associations between dysfunctional attitudes negative symptoms and functioning in schizophrenia. We previously found improvement in experiential negative symptoms and functioning in cognitive-behavioral social skills training (CBSST) in participants with schizophrenia (N = 149), and the present study examined whether improvements in CBSST in that trial were mediated by the group effect on defeatist performance attitudes and asocial beliefs. In multilevel mediation analyses, the effect of treatment group on experiential negative symptoms and functioning was mediated prospectively through defeatist attitudes but asocial beliefs only mediated effects on experiential negative symptoms. The findings suggest that cognitive-behavioral therapy interventions that target dysfunctional attitudes can lead to improvement in negative symptoms and functioning in schizophrenia.