Breastfeeding prevents severe disease in full term female infants with acute respiratory infection.
Breastfeeding prevents severe disease in full term female infants with acute respiratory infection.
复制标题
母乳喂养可以预防患有急性呼吸道感染的足月女婴的严重疾病。
DOI：
10.1097/inf.0b013e31818a8a82
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Polack,FernandoP
中科院分区：
文献类型：
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作者：
Libster,Romina;BugnaHortoneda,Jimena;Laham,FedericoR;Casellas,JavierM;Israele,Victor;Polack,NorbertoR;Delgado,MariaFlorencia;Klein,MariaInes;Polack,FernandoP
背景：母乳喂养是众所周知的预防严重呼吸道感染的保护因素。最近，母乳在极低出生体重婴儿和新生儿中的性别特异性作用被描述：母乳可以保护女孩，但不能保护男孩。目的：确定母乳喂养对足月婴儿急性呼吸道感染严重程度的保护作用对于女孩和男孩是否不同。方法：对因急性呼吸道感染寻求医疗护理的婴儿进行前瞻性横断面研究。通过单变量和多变量分析评估了母乳喂养对病毒性肺炎和住院治疗的保护作用。针对重要的混杂因素对分析进行了调整。结果：共有 323 名患者参加了本研究。母乳喂养可以保护女孩免受肺炎和住院治疗，但不能保护男孩。非母乳喂养的女性特别容易患严重的急性呼吸道感染。结论：母乳喂养对首次出现症状性呼吸道感染的女婴具有预防严重疾病的作用。非母乳喂养的女性患严重急性肺病的风险很高，应重点开展母乳喂养活动。
Background:Breastfeeding is a well-known protective factor against severe respiratory tract infections. Recently, a gender specific role for human milk has been described in very low birth weight infants and neonates: breast milk protected girls but not boys.Objective:To determine whether the protective effect of breastfeeding on the severity of acute respiratory infections in full term infants is different for girls and boys.Methods:A prospective cross-sectional study of infants seeking medical care for acute respiratory infection. The protective role of breastfeeding against viral pneumonia and hospitalization were assessed by univariate and multivariate analyses. Analyses were adjusted for important confounders.Results:A total of 323 patients were enrolled in this study. Breastfeeding protected girls against pneumonia and hospitalization, but did not protect boys. Nonbreastfeeding females were particularly susceptible to severe acute respiratory infections.Conclusions:Breastfeeding had a protective effect against severe disease in infant girls experiencing their first symptomatic respiratory infection. Nonbreastfeeding females are at significant risk for severe acute lung disease and should be targeted intensively by breastfeeding campaigns.