Dental workplace exposure and effect on fertility
Dental workplace exposure and effect on fertility
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DOI：
10.5271/sjweh.436
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发表时间：
1999-06-01
影响因子：
6.3
通讯作者：
Jacobsen, N
中科院分区：
文献类型：
--
作者：
Dahl, JE;Sundby, J;Jacobsen, N
目的 本研究根据报告的牙科材料和技术使用情况评估牙科手术中的职业暴露，并应用怀孕等待时间方法来研究与职业暴露相关的生育力。方法使用自填式邮寄问卷回顾性收集数据，涉及参与者的职业和生育史。研究小组由 558 名女牙科医生和 450 名高中教师组成，她们在挪威生过至少 1 个孩子。本研究包含总共 1408 次怀孕的数据。采用离散比例风险回归法分析了牙科执业和特定工作场所暴露对生育能力的影响。结果大多数女性牙科医生在试图怀孕期间使用汞合金进行补牙，1/3的人每周补牙超过50次。牙齿颜色的填充物使用有限。 75% 的怀孕前，牙科医生报告使用了基于氯仿的根管封闭剂。百分之四十的牙科医生每天都会接触含有乙醇和苯的消毒剂。牙科医生和高中教师之间的生育能力没有差异。接触汞、氯仿和苯与生育能力下降无关，除了汞可能对多产牙科外科医生的最后一次怀孕产生影响之外。结论：职业接触对所研究的女性牙科外科医生的生育能力没有明显的不利影响。
Objectives This study assessed occupational exposure in dental surgeries on the basis of the reported use of dental materials and techniques and applied waiting-time-to-pregnancy methodology to study fertility in relation to the occupational exposure.Methods Data were collected retrospectively using a self-administered postal questionnaire addressing the occupational and reproductive history of the participants. The study groups consisted of 558 female dental surgeons and 450 high school teachers that had given birth in Norway to at least 1 living child. The present study comprised data from a total of 1408 pregnancies. The effects of practicing dentistry and of the given workplace exposure on fertility were analyzed with the discrete proportional hazard regression method.Results Most of the female dental surgeons were using amalgam for fillings during the period they tried to conceive, and 1/3 placed more than 50 fillings a week. Tooth-colored fillings were in limited use. Prior to 75% of the pregnancies, the dental surgeons reported handling chloroform-based root canal sealers. Forty percent of the dental surgeons were daily exposed to disinfectants containing ethanol and benzene. No difference was found in fertility between the dental surgeons and the high school teachers. Exposure to mercury, chloroform, and benzene was not associated with decreased fertility, except for a possible effect of mercury in the last pregnancy of multiparous dental surgeons.Conclusions occupational exposures had no clear adverse effects on fertility among the female dental surgeons studied.