Ultraviolet femtosecond laser creation of corneal flap.

Ultraviolet femtosecond laser creation of corneal flap.
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紫外飞秒激光角膜瓣制作。

DOI:
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发表时间:
2009
影响因子:
2.4
通讯作者:
Christof Dnitzky
Christof Dnitzky
中科院分区:
医学2区
文献类型:
--
作者:
R. Le Harzic;K. König;C. Wüllner;Klaus Vogler;Christof Dnitzky

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目的 研究使用紫外(UV)飞秒激光脉冲进行眼部飞秒激光手术的过程效率和安全性参数。 方法 利用新型掺镱增益介质激光光源对猪眼角膜手术和角膜瓣处理进行了研究。中心波长为345 nm,工作在100 kHz的重复频率的紫外飞秒激光脉冲产生的1035 nm的基本波长的三次谐波。 结果 用低能量脉冲在不到2分钟的时间内形成直径为6 mm、厚度为100 μ m的瓣。在皮瓣处理过程中进行传输和光谱测量。在角膜瓣处理过程中,不到2%的紫外线辐射到达视网膜。紫外光脉冲对视网膜的可见光中心在440 nm的可检测的透射率。 结论 紫外线角膜屈光手术是一种新型手术,考虑到安全性,有可能成为红外线屈光手术的替代方案。
PURPOSE To study parameters for ocular femtosecond laser surgery in terms of process efficiency and safety aspects using ultraviolet (UV) femtosecond laser pulses. METHODS Studies on corneal surgery and flap processing on enucleated porcine eyes were performed using a newly developed ytterbium-doped gain media laser source. Ultraviolet femtosecond laser pulses centered at a wavelength of 345 nm and working at a repetition rate of 100 kHz were generated by the third harmonics of the 1035-nm fundamental wavelength. RESULTS Flaps with a diameter of 6 mm and a thickness of 100 microm were created in less than 2 minutes with low energy pulses. Transmissions and spectral measurements were performed during flap processing. Less than 2% UV radiation reaches the retina during corneal flap processing. A detectable transmittance towards the retina of visible light centered on 440 nm was found for UV pulses. CONCLUSIONS Ultraviolet corneal refractive surgery is a novel procedure and has the potential to be an alternative to infrared refractive surgery considering safety aspects.
DOI: 10.3928/1081-597x-20030101-03
发表时间: 2003
影响因子: 2.4
作者:
L. Nordan;S. Slade;R. N. Baker;C. Suarez;T. Juhász;R. Kurtz
通讯作者: L. Nordan;S. Slade;R. N. Baker;C. Suarez;T. Juhász;R. Kurtz