Reproducibility of coronary calcium quantification in repeat examinations with retrospectively ECG-gated multisection spiral CT
Reproducibility of coronary calcium quantification in repeat examinations with retrospectively ECG-gated multisection spiral CT
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DOI：
10.1007/s00330-002-1394-2
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发表时间：
2002-06-01
影响因子：
5.9
通讯作者：
Becker, CR
中科院分区：
文献类型：
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作者：
Ohnesorge, B;Flohr, T;Becker, CR
在后续检查中，高重复性是冠状动脉钙化评分的关键要求。我们研究了回顾心电门控多层螺旋CT(MSCT)钙化评分的检查重复性。对50例患者进行二次MSCT检查。在舒张期用回溯性心电门控重建，层厚3 mm，时间分辨率高达125ms。我们计算了Agatston评分、有无各向同性内插的钙量和钙质量，并得出了平均值和中位数变异性。我们研究了使用3 mm非重叠和重叠增量(21、1.5、1 mm)时变异性的变化。重叠增量的使用大大降低了扫描间的可变性。我们观察到Agatston评分的最小平均变异性为12%，最小中位变异性为9%。对于体积和质量的量化，我们得到的最小平均变异性为7.5%，最小中位变异性为5%。多层螺旋CT使冠状动脉钙化定量在后续检查中具有很高的重复性，主要基于图像数据，减少了由于重叠增量而产生的部分体积误差。
High reproducibility is a key requirement for coronary calcium scoring in follow-up examinations. We investigated the interexamination reproducibility of calcium scoring with retrospectively ECG-gated multisection spiral CT (MSCT). Fifty patients were examined twice with MSCT. Slices were reconstructed with retrospective ECG gating in the diastolic phase with 3-mm slice width and up to 125-ms temporal resolution. We calculated the Agatston score, calcium volume with and without isotropic interpolation, and calcium mass, and derived the mean and median variability. We investigated the change of variability with use of 3-mm non-overlapping and overlapping increments (21, 1.5, 1 mm). Use of overlapping increment results in considerably reduced interscan variability. We observed a minimum mean variability of 12% and a minimum median variability of 9% for the Agatston score. For volume and mass quantification we obtained a minimum mean variability of 7.5% and a minimum median variability of 5%. Multisection spiral CT enables coronary calcium quantification with high reproducibility in follow-up examinations mainly founded on image data with reduced partial-volume errors due to overlapping increment.