Impact of Impaired Executive Function on Gait Stability
Impact of Impaired Executive Function on Gait Stability
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DOI：
10.1159/000162358
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发表时间：
2008-01-01
影响因子：
2.4
通讯作者：
Beauchet, Olivier
中科院分区：
文献类型：
--
作者：
Allali, Gilles;Assal, Frederic;Beauchet, Olivier
背景：执行功能障碍有助于步态改变，但确切的机制仍然知之甚少。双任务相关的步态变化部分取决于在同时执行的任务之间适当分配注意力的能力，主要与执行缺陷有关。本研究旨在描述执行功能障碍对痴呆患者双任务步态稳定性的影响。方法：采用GAITRite(R)系统测量18例痴呆伴执行功能受损（IEF）、16例痴呆伴执行功能完好（IEF）和22例非痴呆对照（IEF）患者仅行走时、行走伴倒算时（双任务）步幅时间的平均值和变异系数。结果：跨步时间，特别是其变异性，在执行双重任务时显著增加（p < 0.05）。在双重任务中，与非痴呆受试者和无IEF的痴呆受试者相比，IEF仅与行走时的步幅时间和步幅时间变化有关，甚至与更多的步态变化有关。结论：这些发现证实了执行功能在双重任务中的作用，但也强烈表明它们对步态稳定性的重要性。版权所有2008 S. Karger AG，巴塞尔
Background: Executive dysfunction contributes to gait changes, but the precise mechanisms are still poorly understood. Dual-task-related gait changes depend in part on the capacity to appropriately allocate attention between tasks performed simultaneously and are mainly related to executive deficits. This study aimed to describe the impact of dys-executive function on gait stability in subjects with dementia using dual tasking. Methods: Mean values and coefficients of variation of stride time while only walking and while walking and backward counting (dual tasking) were measured using the GAITRite(R) System in 18 subjects with dementia and impaired executive function (IEF), in 16 subjects with dementia and intact executive function, and in 22 nondemented subjects as controls. Results: Stride time, and particularly its variability, significantly increased while performing dual tasking (p < 0.05). IEF was related to both stride time and stride time variability during walking only and to even more gait changes, while dual tasking compared to nondemented subjects and demented subjects without IEF. Conclusions: These findings confirm the role of executive function in dual tasking, but also strongly suggest their importance for gait stability. Copyright (C) 2008 S. Karger AG, Basel