An XmnI polymorphism detected by a human genomic clone from chromosomal band 11p13 [D11S416].
An XmnI polymorphism detected by a human genomic clone from chromosomal band 11p13 [D11S416].
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由人类基因组克隆从染色体带 11p13 [D11S416] 检测到的 XmnI 多态性。
DOI：
10.1093/nar/18.3.689-a
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发表时间：
1990
影响因子：
14.9
通讯作者：
Saunders,GF
中科院分区：
文献类型：
--
作者：
Weil,MM;Huff,V;Compton,DA;Strong,LC;Saunders,GF
克隆来源和描述：pLCXIE 5是一个亚克隆，含有编码人α 2（XI）胶原（COL11A2）基因部分的cos H col11的EcoRI片段（1）。亚克隆检测多态性位点，但不跨越多态性位点。多态性：pLCXIE5可检测到BamH Ⅰ多态性，但扩增片段大小较大（10kb和10kb）。8kb），这使得学习变得困难。BamHl EcoRl双消化将条带大小减小至7.3kb（A1）和6.5kb（A2）。频率：无关的英国白人。A1 0.77，A2 0.23（测试84个染色体）。
Source and Description of Clone: pLCXIE5 is a subclone containing an EcoRIfragment ofcos H col11, coding for part of the human a2 (XI) collagen (COLllA2) gene (1). The subclone detects but does not span the polymorphic site. Polymorphism: A BamHl polymorphism is detectable with pLCXIE5, but the large size of the fragments (10kb andlO. 8kb) makes it difficult to study. A BamHl EcoRl double digest reduces the band sizes to 7.3 kb (Al) and 6.5 kb (A2). Frequency: Unrelated English Caucasians. Al 0.77, A2 0.23 (84 Chromosomes tested).