An evaluation of the diurnal rhythm of urea excretion in healthy young adults.
An evaluation of the diurnal rhythm of urea excretion in healthy young adults.
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健康年轻人尿素排泄昼夜节律的评估。
DOI：
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发表时间：
1981
期刊：
影响因子：
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通讯作者：
V. Young
中科院分区：
文献类型：
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作者：
W. Steffee;C. F. Anderson;V. Young
在健康的年轻人中，尿尿素排泄的日变化已被证明存在。当膳食氮摄入量接近于零时，它的持续性表明，饮食以外的影响可能部分地产生了这种节律。这些可能包括内源性蛋白质周转率的变化，可能是肾小管处理尿素的变化，特别是在膳食氮不足的状态下。在重视疾病状态的变化之前，认识到正常状态下的这些影响是很重要的，特别是当我们获得在医院环境中进行营养干预的能力时。
A diurnal variation in urine urea excretion has been documented to exist in healthy young adults. Its persistence when dietary nitrogen intake approaches zero suggests that influences other than diet may in part generate the rhythm. These may include variations in the efficiency of rates of endogenous protein turnover of perhaps changes in renal tubular handling of urea especially in states of dietary nitrogen inadequacy. Recognition of these effects in the normal state are important before ascribing importance to changes in the disease state, particularly as we gain the ability to intervene nutritionally in the hospital setting.