Switching Off Perceptual Learning: Anodal Transcranial Direct Current Stimulation (tDCS) at Fp3 Eliminates Perceptual Learning in Humans
Switching Off Perceptual Learning: Anodal Transcranial Direct Current Stimulation (tDCS) at Fp3 Eliminates Perceptual Learning in Humans
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DOI：
10.1037/xan0000107
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发表时间：
2016-07-01
影响因子：
1.3
通讯作者：
McLaren, I. P. L.
中科院分区：
文献类型：
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作者：
Civile, Ciro;Verbruggen, Frederick;McLaren, I. P. L.
感知学习可以通过对刺激的体验而获得，否则很难区分，并且通常用误差信号对特征显着性的调节来解释，该误差信号基于构成刺激的其他特征可以预测的程度。在本文中，我们表明 Fp3 处的阳极经颅直流刺激 (tDCS) 直接影响此调制过程，从而消除并可能逆转感知学习。在 2 个实验中，与假刺激（实验 1）或阴极刺激（实验 2）相比，阳极刺激破坏了知觉学习（以反转效应为指标）。我们的研究结果可以解释为表明阳极 tDCS 严重减少甚至废除了基于误差的显着性调制，大大增加了刺激之间的泛化。这一结果支持了基于预暴露导致的显着性变化的感知学习的解释，并开辟了控制这种现象的可能性。
Perceptual learning can be acquired as a result of experience with stimuli that would otherwise be difficult to tell apart, and is often explained in terms of the modulation of feature salience by an error signal based on how well that feature can be predicted by the others that make up the stimulus. In this article we show that anodal transcranial Direct Current Stimulation (tDCS) at Fp3 directly influences this modulation process so as to eliminate and possibly reverse perceptual learning. In 2 experiments, anodal stimulation disrupted perceptual learning (indexed by an inversion effect) compared with sham (Experiment 1) or cathodal (Experiment 2) stimulation. Our findings can be interpreted as showing that anodal tDCS severely reduced or even abolished the modulation of salience based on error, greatly increasing generalization between stimuli. This result supports accounts of perceptual learning based on variations in salience as a consequence of pre-exposure, and opens up the possibility of controlling this phenomenon.