Prognostic factors and relative risk for survival in N1-3 oral squamous cell carcinoma: a multivariate analysis using Cox's hazard model
Prognostic factors and relative risk for survival in N1-3 oral squamous cell carcinoma: a multivariate analysis using Cox's hazard model
复制标题
DOI：
10.1054/bjom.1999.0146
复制
发表时间：
1999-12-01
影响因子：
1.8
通讯作者：
Kohama, G
中科院分区：
文献类型：
--
作者：
Noguchi, M;Kido, Y;Kohama, G
对136例经手术治疗的N1-3口腔鳞状细胞癌患者的临床资料进行回顾性分析，通过多因素分析探讨哪些因素可以预测患者的生存。四个独立因素显著影响生存率的顺序如下：pN期；T台;组织学分级;和N阶段。最显著的是pN期，pN0期患者的5年生存率为91%，pN1-3期患者的5年生存率为41%。我们对80例pN1-3患者进行了进一步的研究，以寻找其生存的预后因素，通过多因素分析确定的独立因素为T期和是否存在囊外转移淋巴结。
The records of 136 patients with N1-3 oral squamous cell carcinoma treated by surgery were investigated retrospectively with the aim of finding out which factors were predictive of survival on multivariate analysis. Four independent factors significantly influenced survival in the following order: pN stage; T stage; histological grade; and N stage. The most significant was pN stage, the five-year survival for patients with pN0 being 91% and for patients with pN1-3 41%. A further study was carried out on the 80 patients with pN1-3 to find out their prognostic factors for survival and the independent factors identified by multivariate analysis were T stage and presence or absence of extracapsular spread to metastatic lymph nodes.