Time to earliest peak serum antibody response to influenza vaccine in the elderly
Time to earliest peak serum antibody response to influenza vaccine in the elderly
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DOI：
10.1128/cdli.4.4.491-492.1997
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发表时间：
1997-07-01
期刊：
影响因子：
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通讯作者：
Lancey, SC
中科院分区：
文献类型：
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作者：
Gross, PA;Russo, C;Lancey, SC
老年人接种流感病毒疫苗后血清抗体水平达到峰值的最早时间尚不明确。我们比较了接种后1周和2周的时间间隔。使用含有流感病毒A/Texas/36/91（H1 N1）、A/Johannesburg/33/94（H3 N2）和B/Harbin/7/94血凝素的市售三价疫苗。对于所有三种疫苗组分，接种后1周的血凝抑制（HAI）抗体滴度显著低于接种后2周的HAI滴度。
The earliest time at which serum antibody levels peak following administration of an influenza virus vaccine in elderly persons is not clearly defined. We compared the time intervals of 1 and 2 weeks after vaccination. A commercial trivalent vaccine containing the hemagglutinins of influenza viruses A/Texas/36/91 (H1N1), A/Johannesburg/33/94 (H3N2), and B/Harbin/7/94 was used. The hemagglutination inhibition (HAI) antibody titers at 1 week after vaccination were significantly lower than the HAI titers at 2 weeks postvaccination for all three vaccine components.