Pulmonary exposure to metal fume particulate matter cause sleep disturbances in shipyard welders
Pulmonary exposure to metal fume particulate matter cause sleep disturbances in shipyard welders
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DOI：
10.1016/j.envpol.2017.09.082
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发表时间：
2018-01-01
影响因子：
8.9
通讯作者：
Lai, Ching-Huang
中科院分区：
文献类型：
--
作者：
Chuang, Hsiao-Chi;Su, Ting-Yao;Lai, Ching-Huang
睡眠障碍可能会给工作场所的工人带来风险。我们的目的是调查金属烟雾细颗粒物 (PM2.5) 与工人睡眠质量之间的关联。我们评估了个人接触金属烟雾 PM2.5 对造船厂焊接工人肺功能、尿液生物标志物和睡眠质量的影响。本研究总共招募了 96 名焊接工人和 54 名办公室工作人员；办公室工作人员接触的PM2.5浓度为82.1+/-94.1μg/m(3)，焊接工人接触的PM2.5浓度为2166.5+/-3149.1μg/m(3)。焊接工人的 FEV25-75 水平显着低于办公室工作人员 (p < 0.05)。在所有工人中，1 μ g/m(3) PM2.5 的增加与尿血清素下降 0.003 ng/mL 相关（95% Cl = -0.007-0.000，p < (105)），在工人中，与尿血清素下降 0.001 ng/mL (95% Cl = 0.004-0.002，p < 0.05) 相关。尿液中的血清素与铜、锰、钴、镍、镉和铅有关，但在办公室工作人员中没有观察到 PM2.5 与尿液中的皮质醇存在显着相关性。与办公室工作人员相比，清醒时间更长（p < 0.05）。我们的研究发现，接触金属烟雾 PM2.5 中的重金属可能会影响焊接工人的睡眠质量 (C) 2017 Elsevier Ltd。保留所有权利。
Sleep disorders may pose a risk to workers in the workplace. We aimed to investigate the associations between metal fume fine particulate matter (PM2.5) and sleep quality in workers. We assessed the effects of personal exposure to metal fume PM2.5 on lung functions, urinary biomarkers, and sleep quality in shipyard welding workers. In total, 96 welding workers and 54 office workers were recruited in the present study; office workers were exposed to 82.1 +/- 94.1 mu g/m(3) PM2.5 and welding workers were exposed to 2166.5 +/- 3149.1 mu g/m(3). Welding workers had significantly lower levels of FEV25-75 than office workers (p < 0.05). An increase in 1 mu g/m(3) PM2.5 was associated with a decrease of 0.003 ng/mL in urinary serotonin (95% Cl = -0.007-0.000, p < (105) in all workers and with a decrease of 0.001 ng/mL in serotonin (95% Cl = 0.004-0.002, p < 0.05) in welding workers, but these were not observed in office workers. There was no significant association of PM2.5 with urinary cortisol observed in any workers. Urinary serotonin was associated with urinary Cu, Mn, Co, Ni, Cd, and Pb. Urinary cortisol was associated with Cu, Mn, Co, Ni, Cd, and Pb. Sixteen subjects were randomly selected from each of the office and welding workers for personal monitoring of sleep quality using a wearable device. We observed that welding workers had greater awake times than did office workers (p < 0.05). Our study observed that exposure to heavy metals in metal fume PM2.5 may disrupt sleep quality in welding workers. (C) 2017 Elsevier Ltd. All rights reserved.