Study of Clinicoradiological Profile in Posterior Reversible Encephalopathy Syndrome: An Experience from North India.
Study of Clinicoradiological Profile in Posterior Reversible Encephalopathy Syndrome: An Experience from North India.
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DOI：
10.5005/jp-journals-10071-24172
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发表时间：
2022
影响因子：
2
通讯作者：
Jeswani, Jitesh
中科院分区：
文献类型：
--
作者：
Goyal, Gourav;Jeswani, Jitesh
可逆性后部脑病综合征（PRES）是一种可逆性疾病。主要病理特征为血管源性脑水肿，以大脑后部受累为主。临床症状包括头痛、癫痫和视力丧失。我们评估了PRES患者的临床放射学特征及其临床结局。一项回顾性研究，纳入了2014年1月至2017年5月的30例病例。在30例患者中，18例为女性，12例为男性。患者的平均年龄为38.6岁。最常见的表现是癫痫发作（66.6%），其次是精神状态改变（53.3%）和头痛（40%）。主要合并症为肾脏疾病（36.7%）、高血压（23.3%）、子痫和产后败血症（26.7%）。最常见的部位是枕顶区（66%）。非典型表现包括颞叶（16%）、基底节（6%）和微出血（6%）。结果良好，死亡率为20%。PRES是一种可逆性疾病，在大多数患者中具有良好的结局。在我们的研究中，癫痫发作是最常见的表现，肾脏疾病是最常见的合并症。Goyal G，Jeswani J.可逆性后部脑病综合征的临床放射学特征研究：来自印度北部的经验。Indian J Crit Care Med 2022;26（4）：501-505.
Posterior reversible encephalopathy syndrome (PRES) is a reversible condition. The Main pathological feature is vasogenic cerebral edema with predominant involvement of posterior part of the cerebrum. Clinical symptoms range from headache, seizure, and vision loss. We evaluated the clinicoradiological features of patients with PRES and their clinical outcome. A retrospective study with 30 cases from January 2014 to May 2017. Of thirty patients, 18 were females and twelve patients were male. The Mean age of the patients was 38.6 years. The most common presentation was seizure (66.6%) followed by altered mental status (53.3%) and headache (40%). The Main comorbid illnesses in our study were renal disease (36.7%), hypertension (23.3%), eclampsia, and postpartum sepsis (26.7%). The Most common site was the occipito-parietal region in the magnetic resonance imaging brain (66%). Atypical presentation involved the temporal lobe (16%), basal ganglia (6%), and microhemorrhage (6%). The Outcome was good with 20% mortalities. PRES is a reversible condition and has a good outcome in most patients. In our study, seizure was the most common presentation and renal disease is the most common comorbid illness. Goyal G, Jeswani J. Study of Clinicoradiological Profile in Posterior Reversible Encephalopathy Syndrome: An Experience from North India. Indian J Crit Care Med 2022;26(4):501–505.
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