The epidemiology of retinal reticular drusen
The epidemiology of retinal reticular drusen
复制标题
DOI：
10.1016/j.ajo.2007.09.008
复制
发表时间：
2008-02-01
影响因子：
4.2
通讯作者：
Klein, Barbara E. K.
中科院分区：
文献类型：
--
作者：
Klein, Ronald;Meuer, Stacy M.;Klein, Barbara E. K.
目的：了解网状性痴呆的患病率、15年累积发病率及危险因素。设计：基于人群的前瞻性研究。方法：1988 - 1990年间纳入4926名43 - 86岁的患者，其中3684人、2764人和2119人分别在威斯康辛州比弗达姆参加了5年、10年和15年的随访检查。主要观察指标包括通过眼底立体彩色照片分级确定的网状结节的患病率和15年发病率。结果：网眼眼珠的基线患病率和15年累积发病率分别为0.7%和3.0%。15年网状结节的发病率随年龄的变化而变化。年龄从43 - 54岁的0.4%上升到75岁及以上的6.6% (P
PURPOSE: To describe the prevalence and 15-year cumulative incidence of and risk factors for reticular drusen.DESIGN: Population-based prospective study.METHODS: Four thousand nine hundred and twenty-six persons, 43 to 86 years of age, were included between 1988 and 1990, of whom 3 684, 2,764, and 2,119 participated in five-, 10-, and 15-year follow-up examinations, respectively, in Beaver Dam, Wisconsin. Main outcome measures included prevalence and 15-year incidence of reticular drusen determined by grading stereoscopic color fundus photographs.RESULTS: The prevalence at baseline and the 15-year cumulative incidence in either eye of reticular drusen was 0.7% and 3.0%, respectively. The 15-year incidence of reticular drusen varied with. age from 0.4% in those 43 to 54 years of age to 6.6% in those 75 years or older at baseline (P