Recent research about mild cognitive impairment in China.
Recent research about mild cognitive impairment in China.
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DOI：
10.3969/j.issn.1002-0829.2014.01.002
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发表时间：
2014-02
期刊：
影响因子：
--
通讯作者：
Xiao S
中科院分区：
文献类型：
--
作者：
Cheng Y;Xiao S
中国人口的快速老龄化激发了人们对痴呆症及其前兆轻度认知障碍（MCI）的病因和预防的研究兴趣。本文综述了近十年来国内MCI的研究进展。MCI的流行病学、神经心理学特征、诊断、遗传病因学、神经影像学和电生理学改变以及治疗等方面的广泛研究提供了一些新的见解，但很少有突破。MCI的预防和治疗的进一步进展将需要更加重视多学科的前瞻性研究，这些研究具有大量的代表性样本，使用标准化方法来评估和监测认知功能随时间的变化。
The rapid aging of the Chinese population has spurred interest in research about the cause and prevention of dementia and its precursor, mild cognitive impairment (MCI). This review summarizes the last decade of research in China about MCI. Extensive research about the epidemiology, neuropsychological characteristics, diagnosis, genetic etiology, neuroimaging and electrophysiological changes, and treatment of MCI has provided some new insights but few breakthroughs. Further advances in the prevention and treatment of MCI will require a greater emphasis on multi-disciplinary prospective studies with large, representative samples that use standardized methods to assess and monitor changes in cognitive functioning over time.