Effects of Mobilization and Tactile Stimulation on Recovery of the Hemiplegic Upper Limb: A Series of Replicated Single-System Studies

Effects of Mobilization and Tactile Stimulation on Recovery of the Hemiplegic Upper Limb: A Series of Replicated Single-System Studies
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DOI:
10.1016/j.apmr.2008.03.016
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发表时间:
2008-10-01
影响因子:
4.3
通讯作者:
Pomeroy, Valerie M.
Pomeroy, Valerie M.
中科院分区:
医学1区
文献类型:
--
作者:
Hunter, Susan M.;Crome, Peter;Pomeroy, Valerie M.

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目的:目的:探讨脑卒中后偏瘫上肢和手部运动功能及运动和触觉刺激障碍的影响。设计:重复的单系统系列,阿坝设计。地点:英国一家社区医院的脑卒中康复病房。参与者:连续性样本,男性和女性(N=6)脑卒中患者(左或右),在发病3个月内。干预:60分钟的日常活动和触觉刺激瘫痪的手臂和手6周,除了通常的康复计划。主要结果测量:局灶性残疾(行动研究手臂测试[ARAT])和运动障碍(运动指数手臂部分)。结果:所有参与者都表现出视觉变化的趋势,水平,或基线和干预阶段的ARAT和运动指数之间的斜率I或更多。通过统计学检验(c统计量和/或Mann-Whitney U检验)证实了6名参与者中5名参与者的目视分析(排除了1名参与者的统计分析)。没有进一步的改善,取得了干预withdrawing.Conclusions:这项研究表明,使用动员和触觉刺激,以提高运动恢复后,严重轻瘫的概念证明,证明进行剂量探索研究作为一个先驱,多中心III期临床试验。
Objective: To explore the effects on motor function and impairment of mobilization and tactile stimulation for the paretic arm and hand after stroke.Design: Replicated single-system series, ABA design.Setting: The stroke rehabilitation ward of a community hospital in the United Kingdom.Participants: Consecutive sample, men and women (N=6) with stroke (left or right), within 3 months of onset.Intervention: Sixty minutes of daily mobilization and tactile stimulation to the paretic arm and hand for 6 weeks in addition to the usual rehabilitation program.Main Outcome Measures: Focal disability (Action Research Arm Test [ARAT]) and motor impairment (Motricity Index arm section).Results: All participants showed visual change in I or more of trend, level, or slope between baseline and intervention phases for both the ARAT and the Motricity Index. The visual analysis was confirmed through statistical testing (c statistic and/or Mann-Whitney U test) for 5 of 6 participants (statistical analysis was precluded for 1 participant). No further improvements were made on intervention withdrawal.Conclusions: This study shows proof of concept for using mobilization and tactile stimulation to improve motor recovery after severe paresis, justifying conducting dose-finding studies as a precursor to multicenter phase III clinical trials.