Adenocarcinoid of the Appendix: Is Right Hemicolectomy Necessary? A Meta-analysis of Retrospective Chart Reviews
Adenocarcinoid of the Appendix: Is Right Hemicolectomy Necessary? A Meta-analysis of Retrospective Chart Reviews
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阑尾腺癌：右半结肠切除术有必要吗？
DOI：
10.1177/000313480407000706
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发表时间：
2004
期刊：
影响因子：
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通讯作者：
D. Franga
中科院分区：
文献类型：
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作者：
B. Varisco;Brian Mcalvin;J. Dias;D. Franga
本研究的目的是比较单纯阑尾切除术和右半结肠切除术治疗局限性阑尾腺癌的疗效。对1966年至2003年3月1日的回顾图表进行文献回顾。根据治疗方式对回顾图表的结果进行评估。使用Hunter-Schmidt荟萃分析方法，通过确定阑尾切除术与扩大切除术的优势比，对研究进行荟萃分析。来自13项研究的100名患者符合纳入标准。单纯阑尾切除术的失败率为7%，扩大切除术的失败率为10%[OR1.9(0.6~5.8)；关联χ21.15，1df，P=0.28]。我们的数据支持在局部的阑尾腺癌样癌病例中单独使用阑尾切除术，前提是没有盲肠受累并且肿瘤的组织学分级较低。
The purpose of this study was to determine the efficacy of simple appendectomy versus right hemicolectomy in the treatment of localized adenocarcinoid of the appendix. A literature review of retrospective chart reviews from 1966 to March 1, 2003, was performed. Outcomes of retrospective chart reviews were assessed on the basis of treatment modality. Meta-analysis of studies by determining odds ratios for appendectomy versus extended resection using the Hunter-Schmidt meta-analytic method was performed. One hundred patients from 13 studies met inclusion criteria. Seven per cent failure rate with appendectomy alone and 10 per cent with extended resection were observed [OR 1.9 (0.6–5.8); association χ2 1.15, 1 df, P = 0.28]. Our data supports the use of appendectomy alone in localized cases of adenocarcinoid of the appendix provided there is no cecal involvement and the tumor's histology is low grade.