Functional connectivity of human chewing: an fcMRI study.
Functional connectivity of human chewing: an fcMRI study.
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人类咀嚼的功能连接：一项 fcMRI 研究。
DOI：
10.1177/0022034512472681
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发表时间：
2013
影响因子：
7.6
通讯作者：
Gerstner,GE
中科院分区：
文献类型：
--
作者：
Quintero,A;Ichesco,E;Schutt,R;Myers,C;Peltier,S;Gerstner,GE
咀嚼是口腔面部最重要的功能之一。咀嚼控制的神经生物学机制已经在动物模型中进行了研究，但在人类中的研究较少。该项目使用功能连接磁共振成像(FcMRI)来评估咀嚼口香糖任务中激活的大脑区域之间的正时间相关性。29名健康的年轻人在咀嚼口香糖时接受了fcMRI扫描程序。以运动皮质和小脑为感兴趣区进行基于种子的fcMRI分析。左右两侧运动皮质与中央后回、小脑、扣带回、楔前叶相互连接和相互连接。小脑种子与对侧小脑半球、双侧感觉运动皮质、左侧颞上回和左侧扣带回有功能性联系。这些结果首次确定了咀嚼过程中参与的功能性中枢网络。
Mastication is one of the most important orofacial functions. The neurobiological mechanisms of masticatory control have been investigated in animal models, but less so in humans. This project used functional connectivity magnetic resonance imaging (fcMRI) to assess the positive temporal correlations among activated brain areas during a gum-chewing task. Twenty-nine healthy young-adults underwent an fcMRI scanning protocol while they chewed gum. Seed-based fcMRI analyses were performed with the motor cortex and cerebellum as regions of interest. Both left and right motor cortices were reciprocally functionally connected and functionally connected with the post-central gyrus, cerebellum, cingulate cortex, and precuneus. The cerebellar seeds showed functional connections with the contralateral cerebellar hemispheres, bilateral sensorimotor cortices, left superior temporal gyrus, and left cingulate cortex. These results are the first to identify functional central networks engaged during mastication.