Detection of the Klebsiella pneumoniae carbapenemase type 2 carbapenem-hydrolyzing enzyme in clinical isolates of Citrobacter freundii and K. oxytoca carrying a common plasmid
Detection of the Klebsiella pneumoniae carbapenemase type 2 carbapenem-hydrolyzing enzyme in clinical isolates of Citrobacter freundii and K. oxytoca carrying a common plasmid
复制标题
DOI：
10.1128/jcm.02038-07
复制
发表时间：
2008-06-01
影响因子：
9.4
通讯作者：
Patel, Jean B.
中科院分区：
文献类型：
--
作者：
Rasheed, J. Kamile;Biddle, James W.;Patel, Jean B.
在密歇根州一家医院从不同患者中回收的弗氏柠檬酸杆菌和产酸克雷伯菌的碳青霉烯类耐药分离株中检测到肺炎克雷伯菌碳青霉烯酶（KPC）。限制性内切酶分析和KPC特异性探针杂交表明，这两个属的bla（KPC-2）基因携带在一个共同的质粒上。
The Klebsiella pneumoniae carbapenemase (KPC) was detected in carbapenem-resistant isolates of Citrobacter freundii and Klebsiella oxytoca recovered from different patients in a Michigan hospital. Restriction analysis and hybridization with a KPC-specific probe showed the bla(KPC-2) genes of these two genera of the family Enterobacteriaceae are carried on a common plasmid.