High-resolution three-dimensional quantitative map of the macromolecular proton fraction distribution in the normal rat brain.
High-resolution three-dimensional quantitative map of the macromolecular proton fraction distribution in the normal rat brain.
复制标题
正常大鼠脑中大分子质子分数分布的高分辨率三维定量图。
DOI：
10.1016/j.dib.2016.11.066
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发表时间：
2017
期刊：
影响因子：
1.2
通讯作者：
Yarnykh,VasilyL
中科院分区：
文献类型：
--
作者：
Naumova,AnnaV;Akulov,AndreyE;Khodanovich,MarinaYu;Yarnykh,VasilyL
所提出的数据集提供了一个规范的高分辨率三维（3D）大分子质子分数（MPF）地图的健康大鼠大脑在体内和源图像用于其重建。使用别处所述的方案（Naumova等人，High-resolution three-dimensional molecular proton fraction mapping for quantitative neuroanatomical imaging of the rodent brain in ultra-high magnetic fields. Neuroimage（2016）doi：10.1016/j.neuroimage.2016.09.036）。使用合成参考图像的单点算法，从具有不同对比度权重（质子密度、T1和磁化转移）的三个源图像重建该图。源图像在11.7 T小动物MRI扫描仪上采集自活体动物，各向同性空间分辨率为170 µ m3，总采集时间约为1.5 h。3D数据集可用于多种目的，包括交互式查看大鼠大脑解剖结构，测量各种大脑结构中的参考MPF值，以及开发用于啮齿动物大脑分割的图像处理技术。它也可以作为一个金标准图像的实施和优化啮齿动物大脑MRI协议。
The presented dataset provides a normative high-resolution three-dimensional (3D) macromolecular proton fraction (MPF) map of the healthy rat brain in vivo and source images used for its reconstruction. The images were acquired using the protocol described elsewhere (Naumova, et al. High-resolution three-dimensional macromolecular proton fraction mapping for quantitative neuroanatomical imaging of the rodent brain in ultra-high magnetic fields. Neuroimage (2016) doi: 10.1016/j.neuroimage.2016.09.036). The map was reconstructed from three source images with different contrast weightings (proton density, T1, and magnetization transfer) using the single-point algorithm with a synthetic reference image. Source images were acquired from a living animal on an 11.7 T small animal MRI scanner with isotropic spatial resolution of 170 µm3and total acquisition time about 1.5 h. The 3D dataset can be used for multiple purposes including interactive viewing of rat brain anatomy, measurements of reference MPF values in various brain structures, and development of image processing techniques for the rodent brain segmentation. It also can serve as a gold standard image for implementation and optimization of rodent brain MRI protocols.