Rong's numbers: accelerating progress in HCV therapeutic research.

Rong's numbers: accelerating progress in HCV therapeutic research.
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荣的数字:加速丙肝治疗研究的进展。

DOI:
10.1126/scitranslmed.3001183
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发表时间:
2010
影响因子:
17.1
通讯作者:
Schooley,RobertT
Schooley,RobertT
中科院分区:
医学1区
文献类型:
--
作者:
Wyles,DavidL;Schooley,RobertT

文献摘要

相似文献

Rong and colleagues have applied a mathematical model of hepatitis C virus (HCV) replication to experimental data from initial clinical investigations of HCV protease inhibitors. In this Perspective, we discuss how mathematical modeling and other modern translational research tools and approaches can be used to expedite drug development with well-designed combination clinical trials that test drugs from multiple collaborators.