Results of the prospective evaluation of radial keratotomy (PERK) study one year after surgery.
Results of the prospective evaluation of radial keratotomy (PERK) study one year after surgery.
复制标题
手术一年后放射状角膜切开术 (PERK) 研究的前瞻性评估结果。
DOI：
10.1016/s0161-6420(85)34054-x
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发表时间：
1985
期刊：
影响因子：
13.7
通讯作者：
Schanzlin,DJ
中科院分区：
文献类型：
--
作者：
Waring3rd,GO;Lynn,MJ;Gelender,H;Laibson,PR;Lindstrom,RL;Myers,WD;Obstbaum,SA;Rowsey,JJ;McDonald,MB;Schanzlin,DJ
放射状角膜切开术的前瞻性评估(PERK)研究是一项关于标准化放射状角膜切开术技术的九中心自身对照临床试验，涉及435例生理性近视患者，这些患者术前屈光度在−2.00到−8.00之间。手术方法：用钻石微米刀切开8个口子，刀刃长度由术中超声测厚确定，中央透明带直径由术前屈光度决定。术后1年，所有患者近视均有下降，正视度数在±1.00度数以内者占60%，低度矫正者占30%，过矫度者占10%(−为4.25~+3.38D)。裸眼视力在20/40或以上者占78%。对于屈光度在−2.00~−4.25之间的患者，手术效果最好。13%的患者失去了一到两条最佳矫正视力。10%的患者散光超过1.00度。临床眩光测试仪没有检测到致残眩光，但有三名患者因眩光而减少了夜间驾驶。在六个月到一年的时间里，19%的眼睛屈光度变化了0.50度。
The Prospective Evaluation of Radial Keratotomy (PERK) study is a nine-center, self-controlled clinical trial of a standardized technique of radial keratotomy in 435 patients who had physiologic myopia with a preoperative refraction between −2.00 and −8.00 diopters. The surgical technique consisted of eight incisions using a diamond micrometer knife with blade length determined by intraoperative ultrasonic pachymetry and the diameter of central clear zone determined by preoperative refraction. At one year after surgery, myopia was reduced in all eyes; 60% were within ±1.00 diopter of emmetropia; 30% were undercorrected and 10% were overcorrected by more than 1.00 diopter (range of refraction, −4.25 to +3.38 D). Uncorrected visual acuity was 20/40 or better in 78% of eyes. The operation was most effective in eyes with a refraction between −2.00 and −4.25 diopters.Thirteen percent of patients lost one or two Snellen lines of best corrected visual acuity. However, all but three eyes could be corrected to 20/20. Ten percent of patients increased astigmatism more than 1.00 diopter. Disabling glare was not detected with a clinical glare tester, but three patients reduced their driving at night because of glare. Between six months and one year, the refraction changed by >0.50 diopters in 19% of eyes.