CORTICAL REPRESENTATION OF MOTION DURING UNRESTRAINED SPATIAL NAVIGATION IN THE RAT
CORTICAL REPRESENTATION OF MOTION DURING UNRESTRAINED SPATIAL NAVIGATION IN THE RAT
复制标题
DOI：
10.1093/cercor/4.1.27
复制
发表时间：
1994-01-01
期刊：
影响因子：
3.7
通讯作者：
GREEN, EJ
中科院分区：
文献类型：
--
作者：
MCNAUGHTON, BL;MIZUMORI, SJY;GREEN, EJ
研究了大鼠感觉运动和后顶叶皮层在八臂径向迷宫任务中与空间无限制运动相关的神经活动。近一半的细胞表现出与运动相关的活动，区分了三种基本的运动模式：左转、右转和向前运动。相关性的范围从强兴奋（相对于静止条件）到强抑制，并以各种不同的方式分布在运动模式之间，例如，区分顺时针和逆时针转动的细胞以拮抗反应或简单的兴奋或抑制来区分。其他人表现出兴奋或抑制相对于转动和静止的条件，因此有选择性的向前运动。许多细胞表现出躯体感觉反应，然而，与其他人的研究结果一致，运动相关性很少能合理地解释躯体感觉反应。此外，运动相关性有时会随着空间背景而变化很大。一些细胞表现出更复杂的运动相关性，例如明显依赖于先前运动的性质，不考虑细胞活动的特定感觉或运动决定因素，这些决定因素在细胞之间变化很大，大鼠的后部新皮层似乎产生了通过空间的身体运动的鲁棒和冗余的内部表示，这样的表示在构建环境的“认知地图”时可能很有用。
Neural activity related to unrestrained movement through space was studied in rat sensorimotor and posterior parietal cortices during performance of an eight-arm, radial maze task, Nearly half of the cells exhibited movement-related activity that discriminated among three basic modes of locomotion: left turns, right turns, and forward motion. Correlates ranged from strong excitation (relative to the still condition) to strong inhibition, and were distributed among the movement modes in a variety of different ways, For example, cells that discriminated between clockwise and counterclockwise turns did so with either antagonistic responses or simple excitation or inhibition. Others showed either excitation or inhibition relative to both turning and the still condition, and hence were selective for forward motion. Many cells exhibited somatosensory responsiveness; however, in agreement with findings of others, motion correlates could rarely be sensibly explained by the somatosensory response. Moreover, movement correlates sometimes varied considerably with spatial context. Some cells exhibited more complex motion correlates, such as an apparent dependence an the nature of the preceding movement, Irrespective of the specific sensory or motor determinants of cell activity, which varied considerably among cells, the posterior neocortex of the rat appears to generate a robust and redundant internal representation of body motion through space, Such a representation could be useful in constructing ''cognitive maps'' of the environment.