DNA Transport and Delivery in Thermal Gradients near Optofluidic Resonators
DNA Transport and Delivery in Thermal Gradients near Optofluidic Resonators
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DOI：
10.1103/physrevlett.108.048102
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发表时间：
2012-01-27
影响因子：
8.6
通讯作者：
Erickson, David
中科院分区：
文献类型：
--
作者：
Serey, Xavier;Mandal, Sudeep;Erickson, David
从理论和实验上研究了硅光子晶体谐振腔附近的热产生及其对DNA输运的影响。在输入功率为10 mW时，温度上升高达57 K。由此产生的光捕获和生物分子传感性能的这些设备被证明是强烈的浮力驱动的流动和热泳的组合的影响。具体地，电磁热点周围的区域由于高自由能势垒而耗尽生物分子。
Heat generation and its impact on DNA transport in the vicinity of an optofluidic silicon photonic crystal resonator are studied theoretically and experimentally. The temperature rise is measured to be as high as 57 K for 10 mW of input power. The resulting optical trapping and biomolecular sensing properties of these devices are shown to be strongly affected by the combination of buoyancy driven flow and thermophoresis. Specifically, the region around the electromagnetic hot spot is depleted in biomolecules because of a high free energy barrier.