Serotonin precursor influenced by type of carbohydrate meal in healthy adults.
Serotonin precursor influenced by type of carbohydrate meal in healthy adults.
复制标题
健康成年人中血清素前体受碳水化合物膳食类型的影响。
DOI：
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发表时间：
1988
影响因子：
7.1
通讯作者：
A. Truswell
中科院分区：
文献类型：
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作者：
P. Lyons;A. Truswell
我们比较了两种不同的碳水化合物膳食(蔗糖或淀粉，120g)和一种脂肪+蛋白质早餐对10名健康成人血浆色氨酸/大分子中性氨基酸(Trp：LNAA)的影响。同时测定血糖和胰岛素水平。两种碳水化合物餐后Trp：LNAA比率均升高(p<0.001)。蔗糖后血糖和胰岛素峰值高于淀粉，Trp：LNAA相应升高(蔗糖+34%和淀粉+20%，p<0.05)。脂肪+蛋白质餐后，这一比例下降了45%。在180min时，碳水化合物(蔗糖0.133和淀粉0.127)的绝对值是脂肪+蛋白质(0.057)的两倍。在晚上提供相同的饭菜时，也发现了类似的结果。我们的结果表明，高碳水化合物膳食对5-羟色胺的合成有影响。我们预测，血糖指数高的碳水化合物比血糖指数低的碳水化合物有更大的5-羟色胺能作用。
We compared the effects on the ratio of plasma tryptophan to large neutral amino acids (trp:LNAA) of two different carbohydrate meals (sucrose or starch, 120 g) and a contrasting meal of fat + protein given at breakfast to 10 healthy adults. Plasma glucose and insulin were also measured. The trp:LNAA ratio rose after both carbohydrate meals (p less than 0.001). Glucose and insulin peaks were higher after sucrose than starch, and trp:LNAA rose correspondingly higher (sucrose +34% and starch +20%, p less than 0.05). The ratio declined 45% after the fat + protein meal. At 180 min, absolute ratio values were twofold higher after carbohydrate (sucrose 0.133 and starch 0.127) than after fat + protein (0.057). Similar results were found with the same meals given in the evening. Our results suggest that high-carbohydrate meals have an influence on serotonin synthesis. We predict that carbohydrates with a high glycemic index would have a greater serotoninergic effect than carbohydrates with a low glycemic index.