BIOCHEMICAL MARKERS OF BONE METABOLISM
BIOCHEMICAL MARKERS OF BONE METABOLISM
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DOI：
10.3109/07853899309147301
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发表时间：
1993-08-01
影响因子：
4.4
通讯作者：
RISTELI, J
中科院分区：
文献类型：
--
作者：
RISTELI, L;RISTELI, J
在本文中，我们回顾了骨代谢标志物的生化基础，并评论了它们的骨特异性和骨组织的代表性。最近取得了重大进展，特别是在骨胶原代谢标志物方面；因此，它们是本次审查的重点。我们还尝试将各种胶原和非胶原标记物彼此联系起来，并与成骨细胞表型的阶段联系起来。
In this article we review the biochemical basis for markers of bone metabolism and comment on their bone specificity and representativeness for bone tissue. Major developments have recently taken place particularly with respect to markers of bone collagen metabolism; accordingly, they are in the focus of this review. We also attempt to relate the various collagenous and non-collagenous markers to each other and to the phases of the osteoblast phenotype.