RESULTS OF OPERATION WITHOUT ADJUVANT THERAPY IN THE TREATMENT OF SMALL-CELL LUNG-CANCER
RESULTS OF OPERATION WITHOUT ADJUVANT THERAPY IN THE TREATMENT OF SMALL-CELL LUNG-CANCER
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DOI：
10.1016/0003-4975(92)90442-7
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发表时间：
1992-09-01
影响因子：
4.6
通讯作者：
GOLDSTRAW, P
中科院分区：
文献类型：
--
作者：
SHAH, SS;THOMPSON, J;GOLDSTRAW, P
手术在小细胞肺癌治疗中的作用仍然是一个争论的话题。我们对转诊给一名外科医生进行分期和治疗的 87 名小细胞肺癌患者进行了回顾性审查。 30 名患者（34.5%）被认为适合开胸手术。 14 名患者患有 I 期疾病，5 名患者患有 II 期疾病，11 名患者患有 III 期疾病。 30 名患者中的 28 名（93.3%）继续接受手术切除。所有接受开胸手术的患者的实际总体 5 年生存率为 43.3%。 I期和III期患者的实际5年生存率分别为57.1%和55.5%。 II期疾病患者没有存活5年。我们的结论是，有一小部分小细胞肺癌患者，经过仔细的术前分期，手术治愈的前景与非小细胞肺癌患者相似。
The role of surgery in the treatment of small cell lung cancer remains a subject of debate. We carried out a retrospective review of 87 patients with small cell lung cancer referred to one surgeon for staging and treatment. Thirty patients (34.5%) were deemed suitable for thoracotomy. Fourteen patients had stage I disease, 5 patients had stage II disease, and 11 patients had stage III disease. Twenty-eight of the 30 patients (93.3%) went on to have surgical resection. The actual overall 5-year survival in all patients who underwent thoracotomy was 43.3%. The actual 5-year survival for patients in stages I and III was 57.1% and 55.5%, respectively. No patients with stage II disease survived 5 years. We conclude that there is a small group of patients with small cell lung cancer in whom, with careful preoperative staging, the prospects of cure by operation are similar to those with non-small lung cancer.