Patient attitudes toward genotyping in an urban women's health clinic.
Patient attitudes toward genotyping in an urban women's health clinic.
复制标题
城市妇女保健诊所患者对基因分型的态度。
DOI：
10.1097/aog.0b013e318187e77f
复制
发表时间：
2008
影响因子：
7.2
通讯作者：
Flockhart,David
中科院分区：
文献类型：
--
作者：
Haas,DavidM;Renbarger,JamieL;Meslin,EricM;Drabiak,Katherine;Flockhart,David
OBJECTIVE: To estimate willingness of women to donate specimens for DNA analysis by needlestick compared with collection of saliva.METHODS: This study was a cross-sectional survey given to women attending clinic appointments asked about their knowledge and attitudes toward genetics research and genotyping.RESULTS: The majority of the 279 women surveyed would give DNA specimens by needlestick (68.3%) but more would be willing to donate saliva (75.7%), P=. 003. An ethnic difference was seen in the replies about needlesticks but not regarding saliva donation. Multivariable analysis demonstrated that women who were likely to donate specimens rated themselves more knowledgeable about genes and DNA (odds ratio 2.43, 95% confidence interval 1.12–5.28) and had graduated from college or higher (odds ratio 6.74, 95% confidence interval 1.98–22.86).CONCLUSION: More women are willing to donate DNA specimens by saliva than by needlestick. Knowledge and higher education predict a willingness to donate.LEVEL OF EVIDENCE: IIIWomen are more likely to donate saliva than blood for genotyping, and knowledge and education level are associated with higher willingness to donate specimens. Supplemental Digital Content is Available in the Text.
