Acoustoelasticity in soft solids:: Assessment of the nonlinear shear modulus with the acoustic radiation force
Acoustoelasticity in soft solids:: Assessment of the nonlinear shear modulus with the acoustic radiation force
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DOI：
10.1121/1.2793605
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发表时间：
2007-12-01
影响因子：
2.4
通讯作者：
Fink, M.
中科院分区：
文献类型：
--
作者：
Gennisson, J. -L.;Renier, M.;Fink, M.
软组织粘弹性特性的评估在医学成像领域受到越来越多的关注，因为病理通常与局部刚度变化有关。迄今为止，该领域的先进技术主要集中在二阶弹性模量（mu）的估计上。本文利用声辐射力诱导组织内远距离产生偏振平面剪切波的超声剪切成像技术，研究了准不可压缩软固体的非线性行为。软固体中应变能的理论研究[Hamilton et al.， J. Acoust.]。Soc。[m. 116, 41-44(2004)]，结果表明，允许恢复高阶弹性模量的著名声弹性实验可以大大简化。实验上，它需要在静态和单轴应力各向同性介质中测量偏振平面横波的局部速度。这些横波速度估计是通过用超快超声扫描仪对横波在软介质中的传播进行成像得到的。在这种情况下，单轴静应力由于非线性效应引起各向异性，并导致横波速度的变化。然后测量了琼脂明胶基和聚乙烯醇基模型的三阶弹性模量(A)。(c) 2007年美国声学学会。
The assessment of viscoelastic properties of soft tissues is enjoying a growing interest in the field of medical imaging as pathologies are often correlated with a local change of stiffness. To date, advanced techniques in that field have been concentrating on the estimation of the second order elastic modulus (mu). In this paper, the nonlinear behavior of quasi-incompressible soft solids is investigated using the supersonic shear imaging technique based on the remote generation of polarized plane shear waves in tissues induced by the acoustic radiation force. Applying a theoretical approach of the strain energy in soft solid [Hamilton et al., J. Acoust. Soc. Am. 116, 41-44 (2004)], it is shown that the well-known acoustoelasticity experiment allowing the recovery of higher order elastic moduli can be greatly simplified. Experimentally, it requires measurements of the local speed of polarized plane shear waves in a statically and uniaxially stressed isotropic medium. These shear wave speed estimates are obtained by imaging the shear wave propagation in soft media with an ultrafast echographic scanner. In this situation, the uniaxial static stress induces anisotropy due to the nonlinear effects and results in a change of shear wave speed. Then the third order elastic modulus (A) is measured in agar-gelatin-based phantoms and polyvinyl alcohol based phantoms. (c) 2007 Acoustical Society of America.