Implementing a large-scale systematic tuberculosis screening program in correctional facilities in South Africa.
Implementing a large-scale systematic tuberculosis screening program in correctional facilities in South Africa.
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DOI：
10.1093/ofid/ofu121
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发表时间：
2015-01
影响因子：
4.2
通讯作者：
Hoffmann CJ
中科院分区：
文献类型：
--
作者：
Zishiri V;Charalambous S;Shah MR;Chihota V;Page-Shipp L;Churchyard GJ;Hoffmann CJ
背景：在南部非洲的教养机构中，结核病的流行率很高。 在南非当地非政府组织的支持下，南非惩教服务部启动了一个系统筛查新入院和现有囚犯症状的方案，然后用GeneXpert结核分枝杆菌/利福平对有症状的囚犯进行微生物检测。方法：我们在5个月的窗口期内进行了项目评估，描述了项目的覆盖范围、有效性、在设施内的采用、成本和可持续性的机会。 这次评估包括4个设施（2个大的和2个小的），每天共普查20 700名囚犯。结果：在2013年5月至9月为期5个月的评估窗口期内，4个设施共筛查了7 426名囚犯。 这意味着筛查了所有新入院者的87%（其余新入院者仅由惩教人员进行筛查，不包括在这些统计数字中）和每日囚犯普查的23%，达到每年计算的整体筛查目标的55%。覆盖范围从这5个月期间在一个较小设施中筛选的57%到最大设施中的13%不等。诊断出201例肺结核病例，占筛查人群的2.1%; 93%记录了结核病治疗的开始。每个结核病病例的费用为1513美元，不包括治疗费用（治疗费用为1880美元）。结论：我们对大量的囚犯进行了高容量筛查，并有效地使用GeneXpert MTB/Rif诊断肺结核并迅速开始治疗。 其成本与其他筛查项目相当。
Background. Tuberculosis (TB) prevalence is high in correctional facilities in southern Africa. With support from local South African nongovernmental organizations, the South African Department of Correctional Services initiated a program of systematically screening newly admitted and current inmates for symptoms followed by GeneXpert Mycobacterium tuberculosis (MTB)/rifampicin (Rif) for microbiologic testing of symptomatic inmates. Methods. We conducted a program evaluation during a 5-month window describing program reach, effectiveness, adoption within the facilities, cost, and opportunities for sustainability. This evaluation included 4 facilities (2 large and 2 smaller) with a total daily census of 20 700 inmates. Results. During the 5-month evaluation window from May to September 2013, 7426 inmates were screened at the 4 facilities. This represents screening 87% of all new admits (the remaining new admits were screened by correctional staff only and are not included in these statistics) and 23% of the daily inmate census, reaching 55% of the overall screening target as calculated per annum. The reach ranged from 57% screened during these 5 months at one of the smaller facilities to 13% at the largest facility. Two hundred one cases of pulmonary TB were diagnosed, representing 2.1% of the screened population; 93% had documented initiation of TB treatment. The cost per TB case identified was $1513, excluding treatment costs (with treatment costs it was $1880). Conclusions. We reached a large number of inmates with high-volume screening and effectively used GeneXpert MTB/Rif to diagnose pulmonary TB and rapidly initiate treatment. The cost was comparable to other screening programs.
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影响因子：
12.7
作者：
Glasgow, RE;Vogt, TM;Boles, SM
通讯作者：
Boles, SM
DOI：
10.5588/ijtld.13.0732
发表时间：
2014-07-01
影响因子：
4
作者：
Harris, J. B.;Siyambango, M.;Reid, S. E.
通讯作者：
Reid, S. E.
影响因子：
168.9
作者：
Mosimaneotsile, B;Talbot, EA;Kenyon, TA
通讯作者：
Kenyon, TA
DOI：
10.1164/rccm.200606-759oc
发表时间：
2007-01-01
影响因子：
24.7
作者：
Wood, Robin;Middelkoop, Keren;Bekker, Linda-Gail
通讯作者：
Bekker, Linda-Gail
影响因子：
3.7
作者：
Henostroza, German;Topp, Stephanie M.;Reid, Stewart E.
通讯作者：
Reid, Stewart E.