Trials and adventures of the synthesis and evaluation of amphiphilic graft copolymers with dynamic topology
Trials and adventures of the synthesis and evaluation of amphiphilic graft copolymers with dynamic topology
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DOI：
10.1002/pol.20220247
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发表时间：
2022-08-01
影响因子：
3.4
通讯作者：
Costanzo, Philip J.
中科院分区：
文献类型：
--
作者：
Kumler, Margaret S.;Skinner, Nicole M.;Costanzo, Philip J.
通过接枝方法制备了具有亲水性主链和疏水性臂的两亲性接枝共聚物。热响应性大分子单体被设计成含有狄尔斯-阿尔德加合物，使得环化逆转将从主链上裂解臂，从而改变聚合物拓扑结构、组成和溶解度。大分子单体通过光诱导原子转移自由基聚合制备，然后通过聚合后改性来安装可聚合官能团。其次，采用自由基聚合得到热响应性两亲性接枝共聚物，其溶液状态的特性进行了广泛的表征，通过UV/维斯光谱和荧光光谱。由于接枝共聚物的两亲性，由于聚集和溶解度限制，出现了一些意想不到的结果。此外，还发现聚（N-异丙基丙烯酰胺）本身具有独特的聚集特性。
Amphiphilic graft copolymers were prepared via a grafting through approach to yield materials with a hydrophilic backbone and hydrophobic arms. The thermally responsive macromonomers were designed to contain a Diels-Alder adduct such that cyclo-reversion would cleave the arms from the backbone thus altering polymer topology, composition and solubility. The macromonomers were prepared via light-inducted atom transfer radical polymerization followed by post-polymerization modification to install a polymerizable functionality. Next, free radical polymerization was employed to yield thermally responsive amphiphilic graft copolymers, whose solution state characteristics were extensively characterized by UV/Vis spectroscopy and fluorimetry. Due to the amphiphilic nature of the graft copolymer, some unexpected results occurred because of aggregation and solubility limitations. Furthermore, it was discovered that poly(N-isopropyl acrylamide) exhibited distinct and unique aggregation properties by itself.