Preferential differences in vaccination decision-making for oneself or one's child in The Netherlands: a discrete choice experiment
Preferential differences in vaccination decision-making for oneself or one's child in The Netherlands: a discrete choice experiment
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DOI：
10.1186/s12889-020-08844-w
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发表时间：
2020-06-01
影响因子：
4.5
通讯作者：
de Wit, G. Ardine
中科院分区：
文献类型：
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作者：
Hoogink, Joram;Verelst, Frederik;de Wit, G. Ardine
背景为了优化荷兰未来公共信息活动的重点，促进成人和儿童接种疫苗，我们量化了几个属性对疫苗接种决策的贡献。方法我们在荷兰成年人中进行了一项离散选择实验（DCE），包括6个属性，即疫苗有效性，疫苗可预防的疾病负担（以严重程度和频率指定），疫苗接种的可及性，共同支付和处方要求，轻微副作用的频率，人口水平的疫苗接种覆盖率和家庭和朋友之间的当地疫苗接种覆盖率。参与者从他们自己的角度（“自己”组）或关于他们最小的孩子的疫苗决定（“孩子”组）回答了DCE。通过面板混合logit模型对数据进行分析。结果我们纳入了1547名成年参与者（825名“自己”和722名“儿童”）。疫苗有效性是“自己”组中最重要的属性，其次是疾病负担（相对重要性（RI）78%）和可获得性（RI 76%）。在“儿童”组中，疾病负担是最重要的，但与疫苗有效性密切相关（RI 97%）。不太重要的是与疫苗有关的轻微副作用的风险以及人口和地方疫苗接种覆盖率。有趣的是，当人群或家人和朋友中的接种率较高时，参与者更愿意接种疫苗，这表明社会影响和社会规范发挥了作用。结论疫苗有效性和疾病严重程度是成年人为自己做决定和父母为孩子做决定的疫苗接种决策的关键属性。因此，成人和儿童疫苗接种的公共宣传活动应主要侧重于这两个属性。此外，还可以考虑加强社会规范。
Background To optimize the focus of future public information campaigns in The Netherlands promoting the uptake of vaccines among adults and children, we quantified the contribution of several attributes to the vaccination decision. Method We performed a discrete choice experiment (DCE) among Dutch adults including six attributes, i.e. vaccine effectiveness, vaccine-preventable burden of disease (specified in severity and frequency), accessibility of vaccination in terms of co-payment and prescription requirements, frequency of mild side-effects, population-level vaccination coverage and local vaccination coverage among family and friends. Participants answered the DCE from their own perspective ('oneself' group) or with regard to a vaccine decision for their youngest child ('child' group). The data was analysed by means of panel mixed logit models. Results We included 1547 adult participants (825 'oneself' and 722 'child'). Vaccine effectiveness was the most important attribute in the 'oneself' group, followed by burden of disease (relative importance (RI) 78%) and accessibility (RI 76%). In the 'child' group, burden of disease was most important, but tied closely with vaccine effectiveness (RI 97%). Of less importance was the risk of mild vaccine-related side-effects and both population and local vaccination coverage. Interestingly, participants were more willing to vaccinate when uptake among the population or family and friends was high, indicating that social influence and social norms plays a role. Conclusions Vaccine effectiveness and disease severity are key attributes in vaccination decision-making for adults making a decision for themselves and for parents who decide for their children. Hence, public information campaigns for both adult and child vaccination should primarily focus on these two attributes. In addition, reinforcing social norms may be considered.