Magnetic resonance imaging in children presenting migraine with aura: Association of hypoperfusion detected by arterial spin labelling and vasospasm on MR angiography findings
Magnetic resonance imaging in children presenting migraine with aura: Association of hypoperfusion detected by arterial spin labelling and vasospasm on MR angiography findings
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DOI：
10.1177/0333102417723570
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发表时间：
2018-04-01
期刊：
影响因子：
4.9
通讯作者：
Proisy, Maia
中科院分区：
文献类型：
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作者：
Cadiot, Domitille;Longuet, Romain;Proisy, Maia
目的对初发有先兆偏头痛的儿童进行磁共振成像（MRI）检查，以排除脑卒中的可能。本研究的目的是报告的血管和脑灌注结果的儿童偏头痛先兆的飞行时间磁共振血管造影术（TOF-MRA）和磁共振灌注成像动脉自旋标记（ASL）。方法我们回顾性地包括所有儿童谁经历了紧急MRI检查与ASL和TOF-MRA序列急性神经功能缺损，并给出了最终诊断偏头痛先兆。ASL灌注图和TOF-MRA图像由对临床数据不知情的审查者独立评估。自动数据后处理后获得每个脑叶的平均脑血流量（CBF）值。在16/17例（94%）儿童中，通过目视评估，在ASL灌注图上发现一个或多个脑叶灌注不足。在TOF-MRA图像上，12/17（71%）例儿童的颅内血管内出现血管痉挛。所有（100%）异常TOF-MRA图像与同侧低灌注有关。平均CBF值显著降低（P
Objective A child presenting with a first attack of migraine with aura usually undergoes magnetic resonance imaging (MRI) to rule out stroke. The purpose of this study was to report vascular and brain perfusion findings in children suffering from migraine with aura on time-of-flight MR angiography (TOF-MRA) and MR perfusion imaging using arterial spin labelling (ASL).Methods We retrospectively included all children who had undergone an emergency MRI examination with ASL and TOF-MRA sequences for acute neurological deficit and were given a final diagnosis of migraine with aura. The ASL perfusion maps and TOF-MRA images were independently assessed by reviewers blinded to clinical data. A mean cerebral blood flow (CBF) value was obtained for each cerebral lobe after automatic data post-processing.Results Seventeen children were finally included. Hypoperfusion was identified in one or more cerebral lobes on ASL perfusion maps by visual assessment in 16/17 (94%) children. Vasospasm was noted within the intracranial vasculature on the TOF-MRA images in 12/17 (71%) children. All (100%) of the abnormal TOF-MRA images were associated with homolateral hypoperfusion. Mean CBF values were significantly lower (P