Genetic evidence for an East Asian origin of domestic dogs
Genetic evidence for an East Asian origin of domestic dogs
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DOI：
10.1126/science.1073906
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发表时间：
2002-11-22
期刊：
影响因子：
56.9
通讯作者：
Leitner, T
中科院分区：
文献类型：
--
作者：
Savolainen, P;Zhang, YP;Leitner, T
家犬起源于狼的说法已经被证实，但其起源事件的数量，以及这些事件发生的时间和地点都不清楚。为了解决这些问题，我们研究了线粒体DNA（mtDNA）序列的变化，在654家犬代表所有主要的狗种群世界各地。虽然我们的数据表明有几个母系起源于狼，但>95%的所有序列属于三个系统发育组，这些组普遍以相似的频率表示，这表明所有狗种群都来自一个单一的基因库。东亚地区的遗传变异比其他地区大，而且地理变异的模式表明家犬起源于东亚，与15,000年前相似。
The origin of the domestic dog from wolves has been established, but the number of founding events, as well as where and when these occurred, is not known. To address these questions, we examined the mitochondrial DNA (mtDNA) sequence variation among 654 domestic dogs representing all major dog populations worldwide. Although our data indicate several maternal origins from wolf, >95% of all sequences belonged to three phylogenetic groups universally represented at similar frequencies, suggesting a common origin from a single gene pool for all dog populations. A larger genetic variation in East Asia than in other regions and the pattern of phylogeographic variation suggest an East Asian origin for the domestic dog, similar to15,000 years ago.