Morbidity and mortality in late preterm infants with severe hypoxic respiratory failure on extra-corporeal membrane oxygenation.
Morbidity and mortality in late preterm infants with severe hypoxic respiratory failure on extra-corporeal membrane oxygenation.
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DOI：
10.1016/j.jpeds.2011.02.015
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发表时间：
2011-08
影响因子：
5.1
通讯作者：
Jain, Lucky
中科院分区：
文献类型：
--
作者：
Ramachandrappa, Ashwin;Rosenberg, Eli S.;Wagoner, Scott;Jain, Lucky
To evaluate morbidity, mortality, and associated risk factors in late preterm term infants (34 0/7-36 6/7 wk) requiring extra-corporeal membrane oxygenation (ECMO). We reviewed a total of 21,218 neonatal ECMO runs in Extracorporeal Life Support Organization (ELSO) registry data from 1986 to 2006. Infants were divided into 3 groups: Late Preterm (34 0/7 to 36 6/7), Early Term (37 0/7 to 38 6/7), and Full Term (39 0/7 to 42 6/7). There were 14,528 neonatal ECMO runs which met inclusion criteria. Late preterm infants experienced the highest mortality on ECMO (late preterm 26.2%, early term 18%, full term 11.2%. p<0.001) and had longer ECMO runs; they also had higher rates of serious complications. GA was a highly significant predictor for mortality. Late preterm infants with a primary diagnosis of sepsis and PPHN had 3-fold higher risk of mortality on ECMO than those with meconium aspiration. Late preterm infants treated with ECMO havehigher morbidity and mortality than term infants. This underscores the need for special consideration of this vulnerable population in the diagnosis and treatment of hypoxic respiratory failure.
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影响因子：
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作者：
Hernandez-Diaz, Sonia;Van Marter, Linda J.;Mitchell, Allen A.
通讯作者：
Mitchell, Allen A.
影响因子：
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MAISELS, MJ;REES, R;FRIEDMAN, Z
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FRIEDMAN, Z
DOI：
10.1016/0002-9378(76)90462-2
发表时间：
1976-01-01
影响因子：
9.8
作者：
HACK, M;FANAROFF, AA;MERKATZ, IR
通讯作者：
MERKATZ, IR