Psoriatic juvenile idiopathic arthritis associated with uveitis: a case report.
Psoriatic juvenile idiopathic arthritis associated with uveitis: a case report.
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DOI：
10.1155/2013/595890
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发表时间：
2013
影响因子：
--
通讯作者：
Simonini G
中科院分区：
文献类型：
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作者：
Moretti D;Cianchi I;Vannucci G;Cimaz R;Simonini G
根据国际流变学协会联盟（ILAR）提出的定义，幼年特发性关节炎（JIA）被定义为病因不明的关节炎，在排除其他已知条件后，开始于16岁以下，持续至少6周。JIA是儿童期最常见的慢性风湿性疾病，被认为是儿童短期和长期获得性残疾的重要原因。目前估计银屑病JIA占所有JIA亚型的10%，慢性葡萄膜炎可能发生在10%至15%的银屑病JIA儿童中。在这份报告中，我们描述了一个病例银屑病JIA并发葡萄膜炎，在儿童失败的非甾体抗炎药，甲氨蝶呤，依那西普治疗。最后，处方阿达木单抗，导致关节炎和葡萄膜炎持续临床缓解。
According to the definition proposed by the International League of Associations for Rheumatology (ILAR), juvenile idiopathic arthritis (JIA) is defined as an arthritis of unknown etiology, starting under 16 years of age and lasting for at least 6 weeks, once other known conditions have been excluded. JIA represents the most common chronic rheumatic disease of childhood and is considered an important cause of short- and long-term acquired disability in children. It is currently estimated that psoriatic JIA represents up to 10% of all JIA subtypes, and chronic uveitis may occur in 10 to 15% of children with psoriatic JIA. In this report we describe a case of psoriatic JIA complicated by uveitis, in a child failing previous treatments with nonsteroidal anti-inflammatory drugs, methotrexate, and etanercept. Finally, adalimumab was prescribed, which led to sustained clinical remission in both arthritis and uveitis.