Coarctation, tubular hypoplasia, and the ductus arteriosus. Histological study of 35 specimens.
Coarctation, tubular hypoplasia, and the ductus arteriosus. Histological study of 35 specimens.
复制标题
缩窄、肾小管发育不全和动脉导管。
作者：
S. Ho;R. Anderson
为了进一步研究动脉导管、主动脉缩窄和主动脉弓管状发育不良之间的关系，进行了一项组织学研究。采用连续切片技术对35个主动脉弓系统进行了研究。其中12个来自患有主动脉缩窄和/或管状发育不良的患者。另外23个心脏来自无主动脉阻塞性病变的患者，其中7个来自解剖结构正常的心脏，其余来自主动脉弓以外其他部位有畸形的心脏。对有主动脉阻塞性病变的心脏进行的解剖学研究强调了区分“主动脉缩窄”和“管状发育不良”的必要性，因为在某些病例中发现主动脉缩窄的帘状病变与管状发育不良同时存在。组织学研究表明，动脉导管很容易与主动脉或肺动脉壁区分开来。在所有这些患有主动脉缩窄或管状发育不良的病例中，在主动脉峡部开口周围都有一个动脉导管组织的吊带。在6个心脏中，看到一个由动脉导管组织构成的隔膜形成了主动脉缩窄病变。
A histological study has been made in an attempt to study further the relation between the ductus arteriosus, coarctation, and tubular hypoplasia of the aortic arch. Thirty-five aortic arch systems were studied using serial sectioning techniques. Twelve were from patients with coarctation and/or tubular hypoplasia. The other 23 hearts were from patients without aortic obstructive lesions, 7 from anatomically normal hearts, and the others from malformed hearts with anomalies elsewhere from the aortic arch. The anatomical study of the hearts with obstructive aortic lesions emphasised the necessity of distinguishing 'coarctation' from 'tubular hypoplasia', since the curtain lesion of coarctation was found to coexist with tubular hypoplasia in some cases. The histological study showed that the ductus was easily distinguished from the walls of the aorta or pulmonary artery. In all these cases with coarctation or tubular hypoplasia a sling of ductal tissue was located around the aortic isthmal orifice. In 6 hearts a diaphragm of ductal tissue was seen to form the coarctation lesion.