Cardiovascular risk among South Asians living in Canada: a systematic review and meta-analysis.
Cardiovascular risk among South Asians living in Canada: a systematic review and meta-analysis.
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DOI：
10.9778/cmajo.20130064
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发表时间：
2014-07-01
期刊：
影响因子：
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通讯作者：
Anand, Sonia S
中科院分区：
文献类型：
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作者：
Rana, Ayesha;de Souza, Russell J;Anand, Sonia S
背景：南亚人约占加拿大人口的3%，与白人相比，某些心血管危险因素和心血管疾病（CVD）的负担更高。本研究的目的是回顾文献，比较成年南亚人和加拿大白人的心血管危险因素和疾病管理措施。方法：检索MEDLINE、Embase、Cochrane和Nursing and Allied Health Literature Cumulative Index数据库自2014年2月17日起至2014年2月17日的文献，并检索所选文章的参考文献列表。在加拿大进行的关于南亚人心血管疾病风险的干预措施和生物学机制观察性研究的英语研究符合纳入条件。在适当的情况下，我们使用随机效应荟萃分析来整合比较南亚人和加拿大白人心血管疾病风险概况的结果。结果：我们纳入了50篇文章（n = 5805313人）。与加拿大白人相比，南亚裔加拿大人的心血管疾病患病率和发病率更高，糖尿病患病率也更高(优势比[OR] 2.25, 95%可信区间[CI] 1.81 ~ 2.80, p
BACKGROUND: South Asians represent about 3% of the Canadian population and have a higher burden of certain cardiovascular risk factors and cardiovascular disease (CVD) compared with white people. The objective of this study was to review the literature to compare cardiovascular risk factors and disease management practices among adult South Asian and white Canadians.METHODS: We searched MEDLINE, Embase, Cochrane and Cumulative Index to Nursing and Allied Health Literature databases from their inception through Feb. 17, 2014 and the reference lists of the selected articles. English-language studies of interventions and observational studies of biological mechanisms underlying CVD risk in South Asians conducted in Canada were eligible for inclusion. Where appropriate, we used random-effects meta-analyses to integrate results comparing the CVD risk profiles of South Asian and white Canadians.RESULTS: We included 50 articles (n = 5805313 individuals) in this review. Compared with white Canadians, South Asian Canadians had a higher prevalence and incidence of CVD, an increased prevalence of diabetes (odds ratio [OR] 2.25, 95% confidence interval [CI] 1.81 to 2.80, p