Synthetic Study on Ecteinascidin 743 Starting from d-Glucose
Synthetic Study on Ecteinascidin 743 Starting from d-Glucose
复制标题
以d-葡萄糖为起始原料的Ecteinascidin 743的合成研究
DOI：
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发表时间：
1999
期刊：
影响因子：
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通讯作者：
T. Fukuyama
中科院分区：
文献类型：
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作者：
A. Endo;T. Kann;T. Fukuyama
在海鞘素743（1）的合成研究过程中，制备了关键中间体5。以D -葡萄糖为原料，通过引入两个氮原子和酚与亚胺的立体选择性加成反应，实现了5的立体控制合成。
: During the course of synthetic study on ecteinascidin 743 ( 1 ), key intermediate 5 was prepared. Stereocontrolled synthesis of 5 from D -glucose was accomplished using incorporation of two nitrogen atoms and stereoselective addition of a phenol to an imine as key steps.